Professionals Urge End to Water Fluoridation

Below abstract indicates fluoride damages of mito of human tooth pulp
cells.

Cytotoxicity of fluoride on human pulp cell cultures in vitro.

OBJECTIVES: Numerous studies have revealed that conventional glass-
ionomer cements might release fluoride into an aqueous environment.
The objective of this study was to examine the effects of fluoride on
human pulp cells in vitro. STUDY DESIGN: H33258 fluorescence, cell
proliferation, protein synthesis, and mitochondrial activity assay
were used to investigate the pathobiological effects of fluoride on
cultured human pulp cells. RESULTS: Fluoride was found to be a
cytotoxic agent to cultured human pulp cells by inhibiting cell
growth, proliferation, mitochondrial activity, and protein synthesis.
CONCLUSIONS: Fluoride release has significant potential for pulpal
toxicity. PMID: 11174602