ParentingBanter.com - View Single Post - Uptake of Hg in *MERCURY* Amalgams-Improvements of removal

"Jan Drew" wrote in message
.. .
http://tinyurl.com/eu2nb

Resolution of orofacial granulomatosis with amalgam removal.

Guttman-Yassky E, Weltfriend S, Bergman R.

Department of Dermatology, Rambam Medical Centre and the Bruce Rappaport
Faculty of Medicine, Haifa, Israel.

A 61-year-old woman presented with a 2-year history of an abnormal
erythematous swelling on the upper lip and cheek. Upon examination there
were no other physical findings. Histological examination found discreet
sarcoidal granulomas in the lower dermis. Routine laboratory studies,
chest radiographs and pulmonary functions were all normal. Clinical
presentation and histological findings were, therefore, compatible with
the diagnosis of orofacial granulomatosis (OFG). The patient was patch
tested with an extended standard series that included metal-salt, dental
prosthesis, bakery and corticosteroids series. The patch test was positive
(score ++) after 48 and 72 h for mercury in the metal-salt and dental
prosthesis series. During the past decade the patient had received amalgam
fillings of several dental cavities, including one adjacent to the swollen
cheek. The unilateral localization of the soft tissue swelling adjacent to
the amalgam tooth fillings, along with the positive patch test for
mercury, raised the possibility that the OFG was part of a delayed
hypersensitive reaction to the fillings. The patient therefore underwent a
total amalgam replacement procedure; complete disappearance of the
swelling overlying the right cheek was observed within 7 weeks and the
swelling of the upper lip subsided completely within 6 months. We propose
that mercury in amalgam tooth fillings is another cause of OFG and suggest
appropriate patch testing in patients who do not have an apparent cause of
OFG.

so....this person was allergic to mercury?? what's your point??

should penicillin never be used because "some" are allergic?? LOL..

also you missed the term "we propose" in the last sentence....ie...they are
guessing

Publication Types:
Case Reports

PMID: 12702083 [PubMed - indexed for MEDLINE]

http://tinyurl.com/jxnjj

Oral lichenoid lesions (OLL) and mercury in amalgam fillings.

Wong L, Freeman S.

Skin and Cancer Foundation, Darlinghurst NSW, Australia.

84 patients with oral lichenoid lesions (OLL) were seen in the contact
dermatitis clinic. All these patients had reticulate, lacy, plaque-like or
erosive lichenoid changes adjacent to amalgam fillings. Patch testing to
metallic mercury, 0.1% thimerosal, 1% ammoniated mercury, 0.1% mercuric
chloride, and in some cases 0.05% phenylmercuric nitrate and amalgam discs
was undertaken. 33 (39%) patients had positive patch test findings. 30/33
patch test positive patients had replacement of their amalgam fillings,
with 28 (87%) patients experiencing improvement of symptoms and signs
within 3 months. This confirms that mercury allergy is a factor in the
pathogenesis of OLL in some cases. In cases where patch test negative
patients improve with amalgam replacement, mercury may be acting as an
irritant in the pathogenesis of OLL.

PMID: 12694209 [PubMed - indexed for MEDLINE]

http://tinyurl.com/lhmpr

Mercury uptake and kinetics after ingestion of dental amalgam.

af Geijersstam E, Sandborgh-Englund G, Jonsson F, Ekstrand J.

Dept. of Basic Oral Sciences, School of Dentistry, Karolinska Institutet,
Huddinge, Sweden.

The aim of the present study was to investigate the G-1 uptake of mercury
(Hg) after intake of a single dose of amalgam-Hg, followed by
pharmacokinetic analysis of the data. Eleven volunteers without amalgam
fillings ingested 1.00 g amalgam powder. Hg in plasma vs. time was
analyzed with a two-compartment model by means of mixed-effects modeling.
A fraction of the absorption rate of Hg to the central compartment was
inversely proportional to the plasma ferritin levels. The population mean
half-life of the terminal phase of Hg in plasma was 37 days, with a
considerable standard deviation in the population. The absorbed fraction
of the administered dose was estimated to be about 0.04%. It is concluded
that the G-1 uptake of Hg is of quantitative importance during dental
treatment.

PMID: 11926235 [PubMed - indexed for MEDLINE]