enigma wrote:
Rosalie B. wrote in
:

My dad was violently (as in debilitating migraines) allergic to
mustard and bananas. I have some allergies to pollen, dust etc.

My niece has just posted that her son has just been taken to the
ER again and this time for a reaction to mango. I don't know
what else he has allergies to, except peanuts. My sister has to
know how to use an epi-pen if she babysits, and my niece's
family severely restricts trips that they will go on because of
her son's allergies.

people with mango allergies are frequently also sensitive to
cashews, as they're related (mangoes & cashews).

My dd#3 has just informed me that her daughter has tested
positive for gluten sensitivity. Also she has 2 genes meaning
that dd#3 has at least one gene and our SIL has one. She
suggested that we might want to consider looking into some of
this stuff and possibly consider getting tested.

to see if you have glutin sensitivities perhaps? obviously one or
both of you carries the gene for it anyway.

This is a misunderstanding. There isn't one gene for it. There are
different genes that contribute to whether or not we become glutin
sensitive. If we become glutin sensitive, this sensitivity may be
expressed differently in different people. Two particular alleles of one
gene have been most closely associated with celiac disease, but other
genes contribute as well.

When I was in medical school, I had one patient who didn't even know she
had a genetic disease (cystic fibrosis) until she was in her mid-40s. In
residency, I had kids who were diagnosed at a few weeks of age. So
having the alleles (versions of a gene) for something doesn't
necessarily mean much.

It is a function of both genetics and environment.

So even if you have a version of a gene that is associated with glutin
sensitivity, it doesn't mean that you will get it or will have a
particular set of symptoms.

Here is an article on the genetics of celiac disease:
http://www.celiac.com/articles/1046/1/Understanding-the-Genetics-of-Gluten-Sensitivity-by-Dr-Scot-Lewey/Page1.html

Most people who have the alleles (version of a gene) for Celiac disease
don't have the disease.

Jeff



I don't know what benefit testing would have for us. How
worried should I be about it? DH is lactose intolerant and one
of my granddaughters has a small amount of that too but I don't
know of any other problems.

do either of you have any problems eating breads? if not, i
wouldn't worry too much about it. if you do, there are lots of
great glutin free options now, so getting a test & getting glutin
out of your diet might make you feel a lot better.
lee