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#62
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Big $$$ for Wakefield's spinning...
(abacus) wrote in message . com...
(Jonathan Smith) wrote in message Sir, I must doff my metaphorical hat to you. This is absolutely the most work anyone has ever put into a response to one of posts. 'tis a real shame that you missed the main thrust of my argument. I feel I must make at least a token response to acknowledge the effort you have put forth. However, I must make this a short post. Please accept the brevity of my response. Now that makes three times I failed to read in between the lines. My apologies sir. I'm sure it is due solely to my own ineptitude in expressing myself clearly and precisely. Clearly. And I posted a quote from her: "Despite the many temptations modern scientists face, they still believe their discipline is self-correcting because it is open, verifiable and subject to close review by scientific peers. In American medicine, however, all three of these pillars are deteriorating." And I asked for the proof - to which you replied: "Yes, of course. The reason she made such a statement must be due to her own bias. It can't possibly be because what she says is true." My point here, sir, was regarding your own bias. You assumed she was biased rather than considering the possibility she was correct. Then you assumed I agreed with her. I do NOT assume she is correct. I merely regard it as plausible hypothesis. Competing data and personal experience plus prior knowledge of sinmilar diatribes gave me reasonable suspicion to suggest that her hypothesis is incorrect. You, on the other hand, immediately jumped to the conclusion that such a statement revealed her bias rather than entertaining the notion that such a hypothesis might be true. As I said, previous information and experience already provided evidentiary support thatt her 1994 hypothesis was (is) incorrect. That, in my opinion, was a sign of your own bias. It is an unbiased estimator based on data. Unfortunately, her hypothesis is hardly testable in the empirical sense. Been pleasant chatting with you sir. Yeh - sure. Next time, defend your position - don't be such a wimp. I made the effort to read the book - now you defend your charawcterization of it: "Cynthia Crossen's "The Tainted Truth" is an excellent expose what can result from the unconscious bias of honest researchers." "The idea that accepting funding for research won't taint the results is IMO a big part of the problem. For more information on this particular issue and how it can bias results, may I suggest the book "Tainted Truth : The Manipulation of Fact In America" by Cynthia Crossen, a reporter and editor for the Wall Street Journal." Like I said - her anecdotes do NOT show this - the three primary anecdotes she proports to show this are innacurate - as I have pointed out. Her conclusion is unsubstantiated. The bulk of her book involves the misuse of research by the MEDIA. Next time when you parade out the journalistic evidence you might first want to check that in fact the evidence is supported and consistent with your argument. js |
#63
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Big $$$ for Wakefield's spinning...
"CBI" wrote in message
hlink.net... JG wrote: "CBI" wrote in message hlink.net... [...CBI's denial of setting up a straw man argument deleted...] I've simply questioned (asked) how extensively Wakefield had developed his "MMR theories" and how much research he (and his colleagues at the RFH) had done *before* the lawyers knocked on his door with their money. Jonathan (and perhaps Mark) apparently believe virtually all, if not absolutely all, occurred *after* Wakefield had accepted the lawyers' money; hell, Jonathan even created a "likely timeline" based on the publication date of the Lancet article. In his reply to this post be gives a pretty convincing one. Okay, I went to Google and found it. He actually has done so in previous posts but you seemt o prefer not to see it. The timeline I saw (before killfiling him) was entirely speculative, nothing more than a conjecture (as to when the receipt of money from the legal aid group occurred) arrived at by working backwards from the date--'98--Wakefield's Lancet article was published. Suffice it to say that the Lawyers cash was involved very early - if not at the very beginning. His exact dates are alot more convincing than your "mid '90's". Uh, Chris, what I'm looking for is some concrete evidence of *when* the (first) payment to Wakefield occurred. Jonathan didn't include this key item in his timeline, and your "Suffice it to say that the Lawyers (sic) cash was involved very early - if not at the very beginning" comment is, well, downright comical given that *it* is considerably less precise than even "the mid-1990s." Comment: Wakefield's theory of an MMR-intestinal disorder link was clearly his own, and it appears that adding autism (as another possible MMR-induced disorder), "by the mid-1990s," was as well. Comment: His reseacrh seems to have looked at wild type virus and Crohn's, not MMR. He seems to have made that leap in the absence of data and was soundl;y trashed for it. IIRC, subsequent research (e.g., by John O'Leary at Trinity University) has shown that the measles virus (in the intestines of kids with autism) is the vaccine strain. Then he moved on to the autism link and it is pretty clear that his interest wasa ccelerated if not inspired by the lawyer's money. Perhaps. ...that have instead tried to take us into this littel side trip about funding of conflict of interest in general. Hey, Chris... Jonathan's the one who seems intent on prolonging a debate about "conflict of interest" and "potential conflict of interest," despite the fact that everyone who's weighed in (including you, if I've understood your views correctly) has tried to explain to him that the disclosure of a conflict of interest DOESN'T annul that conflict of interest. I understand his point and I think the difference between his and mine is largely semantic or theoretical. That isn't the side trip i was talking about. I was referring to bringing in Cherry as a counter example without ever making a concrete statement of what he is an example of ???? Cherry is an example of a researcher/author with a (big-time!) conflict of interest. If I didn't make that clear, the excerpt from the "Money" article certainly should have. ....and then demanding that others do your research for you. No; I've simply asked Jonathan to prove that Cherry has invariably disclosed his financial ties to Lederle (Wyeth) when he's submitted articles for publication. (I don't doubt that he has when he's testified on Lederle's behalf in vaccine-injury lawsuits; i.e., I don't doubt plaintiffs' attorneys have made the relationship known to the court.) Look, the number of articles he's written is finite, so it's not an impossible task. (Where you got the idea that I was asking him to "prove a negative" is beyond me...) But you have brought us back to the original issue. That is that Wakefield hid his conflict of interest. Yes, he undoubtedly did. Again, what I've questioned is the timeline, because it's pertinent, IMO, to the *degree* of guilt: Which came first, Wakefield's theory of an MMR-intestinal disorder-autism link or his receipt of funds from the legal aid group? (If the latter, I suppose it could be claimed that it's entirely the "lawyers and parents theory," *not* Wakefield's. If the former--as the BBC report indicates--Wakefield looks a bit better, though certainly his receipt of funding for a separate, concurrent study should have been divulged *alongside every MMR-related paper/research report he submitted*, to anyone, from the time he accepted the funds onward.) I don't think the BBC study gives enough detail to make any determination. Jonathan's post pretty much nails down his public disclosure about the same time as the legal interest. The "mid-1990s" is less vague than "about the same time"? ....Sure. Uh-huh. of course, ti si not possible to know wha he was working on and not publishing Certainly. but his lack of mention of any data in letters to editors is somewhat telling since it is usuall to cite personal data in such venues if you have it. Very, very weak argument. Only fools would *unquestioningly* accept it if they, or someone for whom they're responsible, might be affected by the information (conclusions/recommendations) presented. And nly fools would unquestioningly reject it just because the guy took a speakers fee. Straw man. I've killfiled the guy. That's interesting. I gotta wonder about the motive. I don't have the time to respond to his tediously protracted posts. He frequently tries to set up hypothetical, "What would you do/say about..."--typically straw man arguments--to either divert attention from a discussion in which he's making little/no headway to one about a tangential topic he [apparently] feels more comfortable discussing. He's insufferably pretentious. We have nothing (more than his own assertions) to show that he has experience in the fields in which he claims to have been involved "in a previous life." He makes wild assumptions about people based on nothing more than his imagination, and he's usually (in my case, thus far *always*) wrong. He's egregiously insulting to anyone who disagrees with (or questions) him (e.g., abacus, Beth). In short, I think he has a huge chip on his shoulder and responding to his diatribes simply isn't worth the time/effort; I have better--more productive--things to do. than to admit that this sacred cow of the anti-vac comunity has turned out to be full of ****. *Might* be, Chris; MIGHT be. (Why would Wakefield be more so than Cherry, who's also accepted funding from *very* interested parties, esp. Lederle? No - definately is. You stil don't get the difference. Wakefield took money and THEN found what they wanted witht he promise of much more to come. Cherry found what the drug companies wanted and THEN took money to tell people about his findings. In one case it seems that findings were purchased. In the other what was purchased was the report of the previous findings. Still speculative (regarding both men). Do you agree with Jonathan; i.e., do you think that simply disclosing a conflict of interest nullifies that conflict of interest, and that failing to disclose a conflict of interest automatically and invariably renders the information "bogus"?) The allegations at hand concern only a undisclosed conflict of interest, not the findings of Wakefield's studies. I don't think you get what he has said. Maybe if you would stop ridiculing him and read what he has to say you would. Bwahahaha! Who ridicules whom, Chris? Get real! And your tendancy to use innuendo rather than plain speach and then back away from your words when challenged has also been noted. (it has also been noted that it is a trick you appear to have learned from Schlafly.) Seems we've discussed "implied" vs. "inferred" a few times already. I understand the difference. What you don't seem to want to admit is that sometimes the inference is so clear that it can be taken as proof of the what is being implied. You're entitled to your opinion, of course. You didn't say his opinion has been purchased but you sure have implied it. Look, Chris, Cherry's opinions regarding pertussis vaccines and vaccination *have* been purchased--he's testified for the defense (i.e., for Lederle) in more than a dozen court cases in which the plaintiffs have alleged (DPT) vaccine-induced damage/death. See above. Wakefield's opinions have been purchased. Conjecture. Circumstantial evidence, nothing more. Cherry's opinions were formed based on good science (unless you have proof to the contrary) and what was purchased was to have him show up and talk about them. - Get it? Yes, but *I* don't think *you* do. You seem to be looking at both situations with an incredible amount of bias. We don't--can't--truly know what either man believed (or the sincerity/depth of his belief), when he first believed (theorized) it, and what prompted his belief. It's *all* speculation/conjecture. 3) Attack the other poster personally. Oh, puhleeze, Chris! I'm a libertarian. I don't believe, as a rule, in the initiation of force (including personal--ad hominem--attacks). Read a few of Jonathan's posts (this thread and others), then go look up "double standard" in a dictionary. Oh puuuuuuhhhleeese - you regularly resort to ad hominem attacks without provocation. I disagree. Huh? When I have "declared the other people are too dense..." (and "sulked" off)? You just did it earlier this post. I did? Your accusations are quite tiresome; shall I add this to your "JG thinks physicians and their associations should be censored" (still unsubstantiated, btw) assertion? No, it was substantiated. I think others would disagree (but then you'd discount their opinions, too). You just refuse to follow any logic more than one step long. Picking up "tricks" from JS? g 1) You claim that the AAP pronouncements dictate government policy. Huh? Sorry, but I'd never (*never*!) claim that a bunch of pediatricians had the power to dictate policy. (Attempt to, yes.) 2) You say there are certain areas where the government should stay out. Damn right. There are numerous such "areas." The gubmnt should confine its activities to those enumerated in the Constitution. 3) Therefore you don't think the AAP should comment on those areas. I've previously explained the difference between "should not" and "must not." I posted links for all of it. Again, you seem to like to express ideas and then try to hide behind the fact that you didn't use specific words. Again, I disagree. I love the English language, including the very precision of certain words. I choose my words carefully/deliberately (especially when debating), and if you don't perceive the nuances, that, IMO, is *your* problem. Non-answer to JS's comments noted. Non-answer? Look, "Money," as I stated, *is* highly regarded. For investment advice - yes. For commentary and reporting on biomedical science - no. Then point out specific, verifiable errors in Rock's article, for heaven's sake! This "my profession's journals are superior" argument is ridiculous. I've no doubt the article was gone over by at least a few editors as well as the magazine's legal advisors. I don't recall hearing of anyone (e.g., Cherry) bringing a libel case in the wake of its publication. What kind of standard is that? I fthe don't sue they admit it's true? In a case such as this, where facts and figures are involved, yes. (Bringing suit is rather extreme. I imagine "they" would simply ask for a public retraction/clarification/apology.) Besides, I am sure what they said is true. I take issue with your interpretation of it. You have made it painfully clear that you don;t know the first things about research grants, gift, and other funding. Actually, I do. I was raised (in large part) in academia, and I served a term on my university's alumni association's board of directors. I also (many years ago, "in a previous life," as JS might say) took a course in accounting for non-profit organizations. A basic issue regarding gifts and grants is who determines how they're used, the donor (restricted grant/gift) or the recipient. You call him pigheaded butthen refuse to back down and drop this area of obvious ignorance. *Sigh*. Consider it dropped. Either way, there is no way your request for information translates into an obligation for JS to do research for you. Besides, the request is unreasonable on the face of it as it is generally considered impossible to prove a negative. "Prove a negative"? *What* negative? Jonathan seems to think Cherry's work (his pertussis vaccine research/related opinions) is "pure"; I've simply asked him to provide evidence that it--by *his* definition that there's no conflict of interest if an author divulges his/her funding sources, for heaven's sake!--is. Right - you are asking him to prove that there is no conflict of interest. That is a negative. No, Chris; I'm asking him to prove that a disclosure of Cherry's ties to vaccine manufacturers (specifically Lederle) has always accompanied his published articles/research studies; i.e., that Cherry's conflict of interest wrt Lederle has regularly been divulged. You've simply twisted it into a negative. Perhaps you don't think JS is up to this herculean task? And besides, like I have said a few time, Cherry is an issue you raised. You have no right to demand that others do yuor research for you. If you wish to say that he has been affected by his conflicts of interest then you should provide evidence. Such as the incontrovertible proof you've provided that Wakefield was "affected" by his conflicts of interest? Goose/gander, Chris! There are simply some things that cannot be proven short of a confession (and then your attorney steps in to have you declared non compos mentis g). If you do not wish to make that claim then the whole thing is a non-sequitur. [...] JG I'm dropping this thread. Enough is enough. ....we are entitled to make almost any reasonable assumption, but should resist making conclusions until evidence requires that we do so. -- Steve Allen |
#64
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Big $$$ for Wakefield's spinning...
"JG" wrote in message ...
"CBI" wrote in message hlink.net... JG wrote: "CBI" wrote in message hlink.net... [...CBI's denial of setting up a straw man argument deleted...] In his reply to this post be gives a pretty convincing one. Okay, I went to Google and found it. He actually has done so in previous posts but you seemt o prefer not to see it. The timeline I saw (before killfiling him) was entirely speculative, nothing more than a conjecture (as to when the receipt of money from the legal aid group occurred) arrived at by working backwards from the date--'98--Wakefield's Lancet article was published. ...and then demanding that others do your research for you. No; I've simply asked Jonathan to prove that Cherry has invariably disclosed his financial ties to Lederle (Wyeth) when he's submitted articles for publication. (I don't doubt that he has when he's testified on Lederle's behalf in vaccine-injury lawsuits; i.e., I don't doubt plaintiffs' attorneys have made the relationship known to the court.) Look, the number of articles he's written is finite, so it's not an impossible task. (Where you got the idea that I was asking him to "prove a negative" is beyond me...) I've killfiled the guy. That's interesting. I gotta wonder about the motive. I don't have the time to respond to his tediously protracted posts. He frequently tries to set up hypothetical, "What would you do/say about..."--typically straw man arguments--to either divert attention from a discussion in which he's making little/no headway to one about a tangential topic he [apparently] feels more comfortable discussing. He's insufferably pretentious. We have nothing (more than his own assertions) to show that he has experience in the fields in which he claims to have been involved "in a previous life." He makes wild assumptions about people based on nothing more than his imagination, and he's usually (in my case, thus far *always*) wrong. He's egregiously insulting to anyone who disagrees with (or questions) him (e.g., abacus, Beth). In short, I think he has a huge chip on his shoulder and responding to his diatribes simply isn't worth the time/effort; I have better--more productive--things to do. For someone you killfiled, you certainly spend a lot of time justifying yourself. Speaking of chips on shoulders, JG. Besides, I am sure what they said is true. I take issue with your interpretation of it. You have made it painfully clear that you don;t know the first things about research grants, gift, and other funding. Actually, I do. I was raised (in large part) in academia, and I served a term on my university's alumni association's board of directors. I also (many years ago, "in a previous life," as JS might say) took a course in accounting for non-profit organizations. A basic issue regarding gifts and grants is who determines how they're used, the donor (restricted grant/gift) or the recipient. Which of course is all relevant to the 1990's. You call him pigheaded butthen refuse to back down and drop this area of obvious ignorance. *Sigh*. Consider it dropped. Right - you are asking him to prove that there is no conflict of interest. That is a negative. No, Chris; I'm asking him to prove that a disclosure of Cherry's ties to vaccine manufacturers (specifically Lederle) has always accompanied his published articles/research studies; i.e., that Cherry's conflict of interest wrt Lederle has regularly been divulged. You've simply twisted it into a negative. Perhaps you don't think JS is up to this herculean task? All original research published by Cherry met the disclosure requirements of the journals in which it was published. Every original research article - every last one of them where Cherry is an author. Every original research article. Not the editorials or the letters to the editor - which of course is not required - these are op eds and reflect the opinion of the author, not the data from a study. JG I'm dropping this thread. Enough is enough. Run and hide - you've been completely and entirely trounced - again. js |
#65
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Big $$$ for Wakefield's spinning...
JG wrote:
"CBI" wrote in message hlink.net... Suffice it to say that the Lawyers cash was involved very early - if not at the very beginning. His exact dates are alot more convincing than your "mid '90's". Uh, Chris, what I'm looking for is some concrete evidence of *when* the (first) payment to Wakefield occurred. Considering that until recently he was denying that they occured at all I think that that degree of precision in the information is not lilely to be forthcomming. JS's time line does narrow it down to a likely date of a year or so. I understand his point and I think the difference between his and mine is largely semantic or theoretical. That isn't the side trip i was talking about. I was referring to bringing in Cherry as a counter example without ever making a concrete statement of what he is an example of ???? Cherry is an example of a researcher/author with a (big-time!) conflict of interest. If I didn't make that clear, the excerpt from the "Money" article certainly should have. We were discussing a guy who took money from lawyers to make a particular finding, found it, and then lied about it. As a counter example you cite a researcher who did his research and then got paid to talk about his findings. ...and then demanding that others do your research for you. No; I've simply asked Jonathan to prove that Cherry has invariably disclosed his financial ties to Lederle (Wyeth) when he's submitted articles for publication. What is the difference. You brought him up. You are saying he is an example of something undesirable. How on earth does that translate into anyone else having to research his actions? It is your point - you research it. Look, the number of articles he's written is finite, so it's not an impossible task. (Where you got the idea that I was asking him to "prove a negative" is beyond me...) You ahve asked that he prove he has never hidden sources of bias. That is a negative. You are losing coherence. But you have brought us back to the original issue. That is that Wakefield hid his conflict of interest. Yes, he undoubtedly did. Again, what I've questioned is the timeline, because it's pertinent, IMO, to the *degree* of guilt: ????? Now who should be laughing? Your grasping at straws is just getting silly. Now you are trying to defend his lying as not being proved to be a big lie - maybe it is just a medium size one? THAT is your defense of the man? Then as a further rebuttal you point to a well respected researcher, point out the obvious (that he has funding), and demand that others prove he is innocence of the same offense as Wakefield? While we are at it should we prove that he doesn't beat his wife as well? but his lack of mention of any data in letters to editors is somewhat telling since it is usuall to cite personal data in such venues if you have it. Very, very weak argument. It only seems weak to someone with a weak grasp of the process. To anyone who has made a carreer of doing and interpretting research it is obvious. Only fools would *unquestioningly* accept it if they, or someone for whom they're responsible, might be affected by the information (conclusions/recommendations) presented. And nly fools would unquestioningly reject it just because the guy took a speakers fee. Straw man. I agree. That is why I turned it around on you. I've killfiled the guy. That's interesting. I gotta wonder about the motive. I don't have the time to respond to his tediously protracted posts. Time (and inclination) to create and respond to tediously protracted posts does not appear to be something you are short of. There must be something else. He frequently tries to set up hypothetical, "What would you do/say about..."--typically straw man arguments--to either divert attention from a discussion in which he's making little/no headway to one about a tangential topic he [apparently] feels more comfortable discussing. You mean like when we are discussing the sins of Wakefield and you bring up Cherry? He's insufferably pretentious. We have nothing (more than his own assertions) to show that he has experience in the fields in which he claims to have been involved "in a previous life." That makes him just like everyone else on usenet. He makes wild assumptions about people based on nothing more than his imagination, And a smattering of facts. and he's usually (in my case, thus far *always*) wrong. No, I find him to be pretty much spot on. Maybe if we were discussing a topic that your were more familiar with you would see it. Face it, the ins and outs of funding, doing, and reporting research is just not something you have a lot of personal experience with. Others do. He's egregiously insulting to anyone who disagrees with (or questions) him (e.g., abacus, Beth). Seems to be a lot of that going around. In short, I think he has a huge chip on his shoulder A lot of that too. and responding to his diatribes simply isn't worth the time/effort; I have better--more productive--things to do. Apparently not. You stil don't get the difference. Wakefield took money and THEN found what they wanted witht he promise of much more to come. Cherry found what the drug companies wanted and THEN took money to tell people about his findings. In one case it seems that findings were purchased. In the other what was purchased was the report of the previous findings. Still speculative (regarding both men). No, one has signifiant evidence about he issue (not the least of which is lies to cover it up) and the other has absolutely no evidence of wrong doing. I don't think you get what he has said. Maybe if you would stop ridiculing him and read what he has to say you would. Bwahahaha! Who ridicules whom, Chris? Get real! Thanks for making my point for me Wakefield's opinions have been purchased. Conjecture. Circumstantial evidence, nothing more. Where there is smoke there is fire. If his funding was on the up and up why did he lie about it? Cherry's opinions were formed based on good science (unless you have proof to the contrary) and what was purchased was to have him show up and talk about them. - Get it? Yes, but *I* don't think *you* do. You seem to be looking at both situations with an incredible amount of bias. We don't--can't--truly know what either man believed (or the sincerity/depth of his belief), when he first believed (theorized) it, and what prompted his belief. It's *all* speculation/conjecture. No, but we know one of them lied about it. 1) You claim that the AAP pronouncements dictate government policy. Huh? Sorry, but I'd never (*never*!) claim that a bunch of pediatricians had the power to dictate policy. (Attempt to, yes.) Oh yes you did. And this time you did use exactly that phrase. I posted a link to the post in the previous thread where you challenged me on the issue (and then you whined because I posted the link to just that post and not the whole thread). Again, you seem to like to express ideas and then try to hide behind the fact that you didn't use specific words. Again, I disagree. I love the English language, including the very precision of certain words. I choose my words carefully/deliberately (especially when debating), and if you don't perceive the nuances, that, IMO, is *your* problem. Oh, I never said the words were not careflly chosen. I think they are very carefully chosen. I give you a lot of credit for your skill in constructing arguments in such a way that you can later wiggle away from them. You learned from the master well. For investment advice - yes. For commentary and reporting on biomedical science - no. Then point out specific, verifiable errors in Rock's article, for heaven's sake! This "my profession's journals are superior" argument is ridiculous. JS and I have already explained that to you. I'm sure his article is factually correct. What we take issue with is your intepretation of certain terms - mostly your lack of understanding about what different sources of funding mean. I've no doubt the article was gone over by at least a few editors as well as the magazine's legal advisors. I don't recall hearing of anyone (e.g., Cherry) bringing a libel case in the wake of its publication. What kind of standard is that? I fthe don't sue they admit it's true? In a case such as this, where facts and figures are involved, yes. (Bringing suit is rather extreme. I imagine "they" would simply ask for a public retraction/clarification/apology.) Oh, please. You have completely lost it. So you believe everything you read unless the subject sues? Right - you are asking him to prove that there is no conflict of interest. That is a negative. No, Chris; I'm asking him to prove that a disclosure of Cherry's ties to vaccine manufacturers (specifically Lederle) has always accompanied his published articles/research studies; i.e., that Cherry's conflict of interest wrt Lederle has regularly been divulged. You've simply twisted it into a negative. Perhaps you don't think JS is up to this herculean task? Explain the difference between proving he has always disclosed his ties and proving that he has never failed to do so? I'm dropping this thread. I would think you should. -- CBI, MD |
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