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Ritalin and Liver cancer



 
 
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  #11  
Old May 7th 05, 02:12 PM
Jeff
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"LadyLollipop" wrote in message
news:qXXee.61476$WI3.15119@attbi_s71...

"Jeff" wrote in message
ink.net...
this was 3 1/2 years ago. Try more modern news next time.

Jeff


Pat reply #
43480324885809348790324899348932948932483094834934-3249348903493248-93-24884

FACT is , it was 3 1/2 years ago, and it is STILL being prescribed!!!!!!!


Which is a good thing for the kids with ADHD. Because methylphenidate is a
safe drug that really helps these kids.

Jeff


  #12  
Old May 7th 05, 02:13 PM
Jeff
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Posts: n/a
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wrote in message
...


wow, very frightening and very relevant for anyone taking ritalin.


Only if their pet mice get some.

Ritalin has never been shown to cause liver cancer in humans. And the dose
was 30 x higher than the maximum dose in humans.

Jeff


  #13  
Old May 7th 05, 03:11 PM
Ilena Rose
external usenet poster
 
Posts: n/a
Default

On Sat, 07 May 2005 13:13:19 GMT, "Jeff"
typical blind, deaf and very, very, very dumb Quack Flack droolings
deleted ...

This idiot has made the ignorant claim that no one has ever been
harmed by 'silicon' (his error) implants. ..

Totally false.

There was probably some VERY good reasons he was never awarded an
unrestricted medical license ... and lies that he is a 'kidsdoc" ...
he NEVER completed a Pediatric residency ... nor had a regular medical
license ... instead ... haunts Usenet with Pro Pharma Propaganda ...




Ritalin and Liver cancer

http://www.preventcancer.com/patient...id/ritalin.htm

American Academy of Pediatrics Guidelines for Treating Behavioral
Disorders in Children with Ritalin Ignores Evidence of Cancer Risks
warns Samuel S. Epstein, M.D.
Chicago, 10/04/01. Based on an industry-funded multi-university trial
on 282 pre-teen children treated with Ritalin for attention
deficit/hyperactivity disorders (ADHD), just published in Pediatrics,
the American Academy of Pediatrics has endorsed the use of the drug.
However, the Academy ignores clear evidence of the drug's cancer risks
of which parents, teachers and school nurses, besides most
pediatricians and psychiatrists, still remain uninformed and unaware.

Some 40 years after the drug was first marketed by Ciba Geigy,
carcinogenicity tests were conducted at the taxpayers expense by the
National Toxicology Program, the results of which were published in
1995. Adult mice were fed Ritalin over a two-year period at dosages
close to those prescribed to children. The mice developed a
statistically significant incidence of liver abnormalities and tumors,
including highly aggressive rare cancers known as hepatoblastomas.
These findings are particularly disturbing as the tests were conducted
on adult, rather than young mice which would be expected to be much
more sensitive to carcinogenic effects. The National Toxicology
Program concluded that Ritalin is a "possible human carcinogen," and
recommended the need for further research. While still insisting that
the drug is safe, the Food and Drug Administration admitted that these
findings signal "carcinogenic potential," and required a statement to
this effect in the drug's package insert. However, these inserts are
not seen by parents or nurses.

The Physicians' Desk Reference admits evidence on the carcinogenicity
of Ritalin, now manufactured by Novartis, qualified by the statement
that "the significance of these results is unknown," apparently not
recognizing that this is more alarming than reassuring. Apart from
cancer risks, there is also suggestive evidence that Ritalin induces
genetic damage in blood cells of Ritalin-treated children.

Concerns on Ritalin's cancer risk are more acute in view of the
millions of children treated annually with the drug and the escalating
incidence of childhood cancer, by some 35% over the last few decades,
quite apart from delayed risks of cancer in adult life. These risks
are compounded by the availability of alternative safe and effective
procedures, notably behavior modification and biofeedback.

There is no justification for prescribing Ritalin, even by highly
qualified pediatricians and psychiatrists, unless parents have been
explicitly informed of the drug's cancer risks. Otherwise, prescribing
Ritalin constitutes unarguable medical malpractice.

CONTACT: Samuel S. Epstein, M.D.

Professor emeritus Environmental & Occupational Medicine

Chairman, Cancer Prevention Coalition


  #14  
Old May 7th 05, 04:02 PM
Ilena Rose
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On Sat, 07 May 2005 13:13:19 GMT, "Jeff"
wrote:

Ritalin has never been shown to cause liver cancer in humans. And the dose
was 30 x higher than the maximum dose in humans.

Jeff



What a despicable Quack Flack Liar this one is:

Adult mice were fed Ritalin over a two-year period at dosages close to those prescribed to children.

  #15  
Old May 7th 05, 04:19 PM
Jeff
external usenet poster
 
Posts: n/a
Default


"Ilena Rose" wrote in message
...
On Sat, 07 May 2005 13:13:19 GMT, "Jeff"
wrote:

Ritalin has never been shown to cause liver cancer in humans. And the dose
was 30 x higher than the maximum dose in humans.

Jeff



What a despicable Quack Flack Liar this one is:

Adult mice were fed Ritalin over a two-year period at dosages close to
those prescribed to children.


I read the actual information, not this quacks interpretation. I don't
consider 30x higher to be "dosages close to those prescribed to children."

Jeff


  #16  
Old May 7th 05, 08:39 PM
David Wright
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Default

In article . com,
Pace Sanders wrote:

David Wright wrote:

Thanks for your comment Jeff but I suspect there are still some out
there who are not aware of the carcinogenicity of Ritalin.


Like you, for example. I could only find two studies on the subject,
both in rats or mice. The conclusion was that there was little
evidence of carcinogenicity from methylphenidate,and in some cases it
actually seemed to *reduce* the instance of tumors.


"a little evidence of carcinogenicity" is enough for me.


You can find a *little* evidence that just about anything is
carcinogenic. However, initial tests often seem to show things that
later turn out not to be true. In any case, this was in mice and
rats, which are often poor models for what happens in humans.

-- David Wright :: alphabeta at prodigy.net
These are my opinions only, but they're almost always correct.
"His staff loves to say Bush is a man who doesn't know the
meaning of the word 'quit.' Well, apparently he's not all
that conversant with the word 'shame' either." (Will Durst)



  #17  
Old May 7th 05, 09:34 PM
Mark Probert
external usenet poster
 
Posts: n/a
Default

Timmy, I read the entire study, and this article ignores 99% of it. Fer
instance, the article leaves out the lack of epidemiological evidence that
the effect is reproduced in humans (there is no proof that it is) and, that
the same study also showed that the incidence of certain types of breast
tumors actually decreased.

Do not rely on journalism for your medical information.

Read the original for yourself. This issue has been hashed, rehashed and
re-re-hashed in mkh, and mha so that it is very old news.

BTW, I wonder why you did not bother to crosspost it to asad, where people
who know this study inside and out, hang out?



"Tim Campbell" wrote in message
oups.com...

http://www.preventcancer.com/patient...id/ritalin.htm

American Academy of Pediatrics Guidelines for Treating Behavioral
Disorders in Children with Ritalin Ignores Evidence of Cancer Risks
warns Samuel S. Epstein, M.D.

Chicago, 10/04/01. Based on an industry-funded multi-university trial
on
282 pre-teen children treated with Ritalin for attention
deficit/hyperactivity disorders (ADHD), just published in Pediatrics,
the American Academy of Pediatrics has endorsed the use of the drug.
However, the Academy ignores clear evidence of the drug's cancer risks
of which parents, teachers and school nurses, besides most
pediatricians
and psychiatrists, still remain uninformed and unaware.

Some 40 years after the drug was first marketed by Ciba Geigy,
carcinogenicity tests were conducted at the taxpayers expense by the
National Toxicology Program, the results of which were published in
1995. Adult mice were fed Ritalin over a two-year period at dosages
close to those prescribed to children. The mice developed a
statistically significant incidence of liver abnormalities and tumors,
including highly aggressive rare cancers known as hepatoblastomas.
These
findings are particularly disturbing as the tests were conducted on
adult, rather than young mice which would be expected to be much more
sensitive to carcinogenic effects. The National Toxicology Program
concluded that Ritalin is a "possible human carcinogen," and
recommended
the need for further research. While still insisting that the drug is
safe, the Food and Drug Administration admitted that these findings
signal "carcinogenic potential," and required a statement to this
effect
in the drug's package insert. However, these inserts are not seen by
parents or nurses.

The Physicians' Desk Reference admits evidence on the carcinogenicity
of
Ritalin, now manufactured by Novartis, qualified by the statement that
"the significance of these results is unknown," apparently not
recognizing that this is more alarming than reassuring. Apart from
cancer risks, there is also suggestive evidence that Ritalin induces
genetic damage in blood cells of Ritalin-treated children.

Concerns on Ritalin's cancer risk are more acute in view of the
millions
of children treated annually with the drug and the escalating incidence

of childhood cancer, by some 35% over the last few decades, quite apart

from delayed risks of cancer in adult life. These risks are compounded
by the availability of alternative safe and effective procedures,
notably behavior modification and biofeedback.

There is no justification for prescribing Ritalin, even by highly
qualified pediatricians and psychiatrists, unless parents have been
explicitly informed of the drug's cancer risks. Otherwise, prescribing
Ritalin constitutes unarguable medical malpractice.

CONTACT: Samuel S. Epstein, M.D.

Professor emeritus Environmental & Occupational Medicine

Chairman, Cancer Prevention Coalition

c/o University of Illinois at Chicago

School of Public Health, M/C 922

2121 W. Taylor Street

Chicago, IL 60612

phone 312-996-2297, fax 312-413-9898

email



  #18  
Old May 7th 05, 09:35 PM
Mark Probert
external usenet poster
 
Posts: n/a
Default


"Tim Campbell" wrote in message
ups.com...

Jeff wrote:
this was 3 1/2 years ago. Try more modern news next time.

Jeff


Thanks for your comment Jeff but I suspect there are still some out
there who are not aware of the carcinogenicity of Ritalin.


True. There are those of us who read the actual study and know that there is
no carcinogenicity in humans. Just specially bred mice.



  #19  
Old May 7th 05, 09:42 PM
Mark Probert
external usenet poster
 
Posts: n/a
Default


"LadyLollipop" wrote in message
news:w8Yee.61498$WI3.18364@attbi_s71...

"David Wright" wrote in message
...
In article . com,
Tim Campbell wrote:

Jeff wrote:
this was 3 1/2 years ago. Try more modern news next time.

Jeff

Thanks for your comment Jeff but I suspect there are still some out
there who are not aware of the carcinogenicity of Ritalin.


Like you, for example. I could only find two studies on the subject,
both in rats or mice. The conclusion was that there was little
evidence of carcinogenicity from methylphenidate,and in some cases it
actually seemed to *reduce* the instance of tumors.

-- David Wright :: alphabeta at prodigy.net
These are my opinions only, but they're almost always correct.


INCORRECT


Actually, very correct. I read both studies that David reference, in their
entirety, and what he said is *exactly* correct.


http://www.pharma.us.novartis.com/pr...ritalin-sr.pdf


On page 4 it points out that the daily dose used in the study was approx. 60
mg/kg/day which is 30 times the MAXIMUM recommended daily dose. Since MPH is
rapidly cleared from the system, there is no possibility of a cumulative
effect.

These are the F A C T S from a website that you posted as authorative and
supporting your claim that David is incorrect. Actually they prove you
wrong, and prove him wRIGHT.


  #20  
Old May 7th 05, 09:43 PM
Mark Probert
external usenet poster
 
Posts: n/a
Default


"Pace Sanders" wrote in message
ups.com...

David Wright wrote:

Thanks for your comment Jeff but I suspect there are still some out
there who are not aware of the carcinogenicity of Ritalin.


Like you, for example. I could only find two studies on the subject,
both in rats or mice. The conclusion was that there was little
evidence of carcinogenicity from methylphenidate,and in some cases it
actually seemed to *reduce* the instance of tumors.


"a little evidence of carcinogenicity" is enough for me.


find and read the study.


 




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