Mercury in Vaccines

I had put Peter back in my ignore list... so I wouldn't have seen his
reply had you not replied to him, Jan. Peter is turning in to a
regular laughing stock. Once again, he didn't even bother to click on
the provided link before shooting his mouth off. Had he resisted the
temptation to be lazy and taken less than 1 second to click on the link
I provided, he would have seen that the title of the study in question
is "Thimerosal and Animal Brains: New Data for Assessing Human
Ethylmercury Risk"

Let's post that again on it's own line so everyone can see how
incredibly lazy and ignorant Peter is:

"Thimerosal and Animal Brains: New Data for Assessing Human
Ethylmercury Risk"

Now let's emphasize a couple of words. ***ETHYLMERCURY RISK***

Pointing out Peter's ineptitude is like shooting fish in a barrel.
That's why I put him in my ignore list. There's just no challenge.

Max.


Jan Drew wrote:
And where does the word "ethylmercury" appear in the above? (Perhaps I
can't see it. After all, I have to rely on Google to find things.)

He didn't need to. He gave all enought credit to know what *inorganic* and
*organic*
and *total*mercury meant.

Feel free to tell us that "inorganic mercury" is "ethylmercury". We
need a good laugh.

Sadly..the the laugh is about your ignorance.

http://www.checnet.org/healthehouse/...sp?Main_ID=472

Common Names: elemental mercury, quicksilver, colloidal mercury, metallic
mercury

Mercury is a toxic heavy metal that is found naturally in the environment.
As the result of human activities, environmental levels have increased
substantially over natural levels. Mercury is found in three forms: organic,
inorganic and elemental (mercury).

Mercury is a potent neurotoxin that can cause permanent damage to the brain
and central nervous system, especially among young children. In pregnant
women, mercury can pass through the placenta and can harm the fetus.

Mark Probert wrote:
Mercury in Vaccines

What vaccines? It has been removed! This is like complaining about Nixon
being president.

That's only partially correct. Thimerosal is still in flu shots.
http://www.cdc.gov/flu/about/qa/thimerosal.htm

And flu shots are now recommended for infants.
http://www.prnewswire.com/cgi-bin/st...02163256&EDATE

Max C. wrote:
Mark Probert wrote:
Mercury in Vaccines
What vaccines? It has been removed! This is like complaining about Nixon
being president.

That's only partially correct. Thimerosal is still in flu shots.
http://www.cdc.gov/flu/about/qa/thimerosal.htm

And flu shots are now recommended for infants.
http://www.prnewswire.com/cgi-bin/st...02163256&EDATE


But the anti-vac liars used to whinny and whine that it was the
cumulative effects of all those shots that caused the "autism epidemic"
and not just a single shot.

Mark Probert wrote:
Max C. wrote:
Mark Probert wrote:
Mercury in Vaccines
What vaccines? It has been removed! This is like complaining about Nixon
being president.

That's only partially correct. Thimerosal is still in flu shots.
http://www.cdc.gov/flu/about/qa/thimerosal.htm

And flu shots are now recommended for infants.
http://www.prnewswire.com/cgi-bin/st...02163256&EDATE


But the anti-vac liars used to whinny and whine that it was the
cumulative effects of all those shots that caused the "autism epidemic"
and not just a single shot.

There is some evidence that autism rates are going down, but it has
been disputed. Then again, maybe there is no connection at all. There
has been no large scale study to prove one way or another. That's all
beside the point. My reason for posting is to address the fact that
infants could still be getting thimerosal in their vaccine schedule.

As John pointed out above:

Dr. George Lucier, toxicologist and former director of the
Environmental
Toxicology Program, National Institute of Environmental Health Sciences
says, "Thimerosal contains organic mercury. Organic mercury is a known
developmental neurotoxin and the fetus and infants are at special risk.
Public health policies should not allow infants to be purposely
injected
with organic mercury."

Max.

I would be interested in your comments. Enjoy your day.

Roman Bystrianyk, "Thimerosal neurotoxicity and protection with
N-Acetylcysteine supplementation", Health Sentinel, January 3, 2005,

In the 1930s, Eli Lily developed Thimerosal as a preservative and it
was widely used in vaccines. Until the removal of Thimerosal, which
contains 49.9% ethyl mercury by weight, from most pediatric vaccines in
2001, the source of the largest human exposure to mercury in the US was
in children under 18 months of age undergoing routine childhood
immunization schedules. Before 2001, a child may have received a
cumulative dose of over 200 µg/kg (micrograms per kilogram) in the
first 18 months of life.

Although Thimerosal has been removed from most childhood vaccines, it
is still present in the flu vaccine, which is given to pregnant women,
the elderly, and children. Also, many vaccines given to children in
developing countries still contain Thimerosal.

In the 2005 issue of NeuroToxicology, the authors of a study examine
the toxicity of Thimerosal within the body including neurons. They
examine the neurotoxic mechanisms, how the body detoxifies mercury, and
the use of N-Acetylcysteine, or NAC for short, in facilitating the
detoxification pathway within the body.

Glutathione, a tripeptide composed of cysteine, glutamate, and glycine,
is manufactured in the liver and also in the brain. Normally, the
concentrations of glutathione in the cells are quite high providing for
detoxification of a variety of heavy metals including mercury. However,
when this essential antioxidant is depleted the excess mercury can bind
to internal cellular proteins leading to toxic damage. Studies have
shown that, "low micromolar concentrations of Thimerosal induced DNA
strand breaks, caspase-3 activation, membrane damage and cell death."

Although the brain can produce glutathione, it can only manufacture
this from its immediate precursor cysteine. The liver, on the other
hand, is able through a long series of biochemical steps to create
glutathione from methionine. Methionine is an essential amino acid that
supplies the body with sulfur and methyl groups. The liver uses a
number of enzyme systems along with various B vitamins to produce
glutathione. The liver then exports the glutathione to the blood that
then is broken down to cystine. Cystine crosses the blood-brain barrier
to be used by the brain to make glutathione. Thus, the brain is reliant
on the liver to manufacture chemicals to keep it free from toxins.

The brain contains neurons and other cells called astrocytes.
Astrocytes use the cystine that crosses the blood-brain barrier to make
glutathione. The astrocytes then export the glutathione to the space
between the cells where it is broken down to cysteine. The neurons take
up the cysteine and manufacture glutathione. This complex series of
biochemical events is what is necessary to keep the brain free from
heavy metal damage.

The authors first examined the level of Thimerosal that would cause
toxic damage to cells. They found that the higher the concentration of
Thimerosal the greater the number of cells that were killed although
the nerve cell response occurred with only a 3 hour exposure, whereas
the other cell line required a 48 hour exposure demonstrating that
nerve cells are more sensitive to Thimerosal toxicity. "In both cell
lines, a progressive increase in cytotoxicity (decrease in viability)
was observed when Thimerosal dose was progressively doubled from 2.5
µmol/L [micromoles per liter] to 5, 10, and 20 µmol/L. Viability was
reduced more than 50% in both cell lines with exposure to 10 µmol/L
Thimerosal and less than 10% of cells survived a dose of 20 µmol/L."

The authors then pretreated cells with NAC before adding a dose of 15
µmol/L Thimerosal. They found that, "Thimerosal alone induced more
than a 6-fold decrease in viability", and that NAC, "provided
significant protection against cell death". The authors note,
"Thimerosal induces oxidative stress and apoptosis by activating
mitochondrial cell death pathways. A subsequent study using cultured
human neuron and fibroblast cell lines similarly showed that low
micromolar concentrations of Thimerosal induced DNA strand breaks,
caspase-3 activation, membrane damage and cell death."

The authors conclude that, "numerous clinical studies have
demonstrated the efficacy of NAC in increasing intracellular
glutathione levels and reducing oxidative stress in humans. Since
cytotoxicity with both ethyl- and methyl- mercury have been shown to be
mediated by glutathione depletion, dietary supplements that increase
intracellular glutathione could be envisioned as an effective
intervention to reduce previous or anticipated exposure to mercury.
This approach would be especially valuable in the elderly and in
pregnant women receiving Rho D immunoglobulin shots, and individuals
who regularly consume mercury-containing fish."

SOURCE: NeuroToxicology, Vol. 26, 2005, pp. 1-8

Peter Bowditch. insists on showing his further ignorance wrote:
"Jan Drew" wrote:


"Peter Bowditch" wrote in message
. ..
"Max C." wrote:

Jeff wrote:
This assumption is a bad assumption. Methylmercury is actively taken
into
the brain; Ethylmercury is not. So the toxicity of ethylmercury is a
lot
less.

Wow. That is absolutely wrong. Ethylmercury does, in fact, make its
way into the brain.

http://www.pubmedcentral.nih.gov/art...?artid=1280369
"Brain concentrations of total mercury were approximately 3-4 times
lower in the thimerosal group than in the methylmercury group, and
total mercury cleared more rapidly in the thimerosal group (with a
half-life of 24.2 days versus 59.5 days). However, the proportion of
inorganic mercury in the brain was much higher in the thimerosal group
(21-86% of total mercury) compared to the methylmercury group
(6-10%). Brain concentrations of inorganic mercury were approximately
twice as high in the thimerosal group compared to the methylmercury
group. Inorganic mercury remains in the brain much longer than organic
mercury, with an estimated half-life of more than a year. It's not
currently known whether inorganic mercury presents any risk to the
developing brain."

And where does the word "ethylmercury" appear in the above? (Perhaps I
can't see it. After all, I have to rely on Google to find things.)

He didn't need to. He gave all enought credit to know what *inorganic* and
*organic*
and *total*mercury meant.

He did need to. He started off talking about ethylmercury, which is a
very specific chemical compound (despite what Saint Boyd might say).

There is no Saint Boyd. There is Dr. Boyd Haley who is a Ph.D chemist..
who has done much research on mercury, including thimerosal.

In FACT..the one who you have LIES about on you website.

http://www.altcorp.com/DentalInformation/thimerosal.htm

He then quoted something which made a distinction between
methylmercury and "inorganic mercury". I know what "inorganic mercury"
means, and it doesn't mean "ethylmercury"


Feel free to tell us that "inorganic mercury" is "ethylmercury". We
need a good laugh.

Sadly..the the laugh is about your ignorance.

http://www.checnet.org/healthehouse/...sp?Main_ID=472

Common Names: elemental mercury, quicksilver, colloidal mercury, metallic
mercury

All of which are common names for something which is not ethylmercury.

Ethymercury IS in thirmerosal. It does go to the brain.

Mercury is a toxic heavy metal that is found naturally in the environment.
As the result of human activities, environmental levels have increased
substantially over natural levels. Mercury is found in three forms:
organic,
inorganic and elemental (mercury).

Mercury is a potent neurotoxin that can cause permanent damage to the
brain
and central nervous system, especially among young children. In pregnant
women, mercury can pass through the placenta and can harm the fetus.


http://www.scorecard.org/chemical-pr...e_id=EDF%2d173

Did you read the next bit you pasted? The bit where it lists
ethylmercury under the heading "Organic Mercury Compounds". Doesn't
this tell you that ethylmercury cannot be "inorganic mercury"?

Do you understand what the prefix "ethyl-" means?

I KNOW more about MERCURY than you do..I was POISONED by it from
AMALGAMS and came close to dying!

http://www.greenfacts.org/glossary/def/ethylmercury.htm

Ethylmercury
Similar term(s): EtHg

Definition:
C2H5Hg+. Ethylmercury is a cation that forms organic mercury compounds
such as ethylmercury chloride and ethylmercury urea. Thimerosal is also an
ethylmercury salt: sodium ethylmercuric thiosalicylate. The term
'ethylmercury' is sometimes used as a generic term to describe ethylmercury
compounds.




ORGANIC MERCURY COMPOUNDS
CAS Number: EDF-173


Note that ORGANIC MERCURY COMPOUNDS may include any of the following
constituents:
ALKYL MERCURY COMPOUNDS
ARYL MERCURY COMPOUNDS
BIS(ISOBUTYL) MERCURY
CHLOROMETHOXYPROPYLMERCURIC ACETATE [CPMA]
DI(PHENYLMERCURY)DODECENYLSUCCINATE [PMDS]
DIETHYL MERCURY
DIISOPROPYL MERCURY
DIMETHYL MERCURY
ETHYLMERCURIC PHOSPHATE
HYDROXYMETHYL MERCURY
MERCURIC ACETATE
METHOXYETHYLMERCURIC ACETATE
METHYL MERCURY
METHYL MERCURY CHLORIDE
METHYL MERCURY COMPOUNDS
METHYLMERCURIC DICYANAMIDE
PHENYL MERCURIC PROPIONATE
PHENYLMERCURIC ACETATE
PHENYLMERCURIC OLEATE [PMO]
THIMEROSAL


It makes it OUT of the brain faster than Methylmercury, but there is no
data proving that a quicker exit relates to zero damage.

A pediatric dose of hepatitis B vaccine contains 12.5 micrograms.
The
major toxicity of mercury is manifested in the central nervous
system.

Except that ethylmercury, in the doses used, has never been shown to
be
harmful the human brain.

Just because something "has not been shown" does not mean it isn't so.
It simply means the right study has not been performed. Can you please
show us a broad study comparing 100% unvaccinated children with
vaccinated children that compare the gambit of possible risk factors of
thimerosal such as autism, ADD/ADHD, asthma and several
neurodegenerative disorders? To my knowledge, such a study does not
exist. That being the case, it's no wonder "it has never been shown."

Yet, there still is no evidence that the amount of ethylmercury in
vaccines
is dangerous.

There's plenty of evidence. It just so happens that, at this time,
it's all anecdotal. As I said, the proper studies have not been done.

Max.
--
Peter Bowditch

Show us your further IGNORANCE...Peter!

You didn't bother to click on the link..Max gave.

http://www.pubmedcentral.nih.gov/art...?artid=1280369

"Thimerosal and Animal Brains: New Data for Assessing Human
Ethylmercury Risk"

Max C. wrote:
Mark Probert wrote:
Max C. wrote:
Mark Probert wrote:
Mercury in Vaccines
What vaccines? It has been removed! This is like complaining about Nixon
being president.
That's only partially correct. Thimerosal is still in flu shots.
http://www.cdc.gov/flu/about/qa/thimerosal.htm

And flu shots are now recommended for infants.
http://www.prnewswire.com/cgi-bin/st...02163256&EDATE

But the anti-vac liars used to whinny and whine that it was the
cumulative effects of all those shots that caused the "autism epidemic"
and not just a single shot.

There is some evidence that autism rates are going down, but it has
been disputed.

The reason that it is disputed is that the "evidence" datasets used are
not designed to make such evaluations. Thus, there is no evidence that
the autism rates are going down.

Recently, Shattuck showed that there may be no evidence that the autism
rates actually went up. Of course, the anti-vac liars immediately
trashed him, as they have a vested interest in the so-called autism
epidemic.

Then again, maybe there is no connection at all. There
has been no large scale study to prove one way or another. That's all
beside the point. My reason for posting is to address the fact that
infants could still be getting thimerosal in their vaccine schedule.

Like I said, one shot. Period. It was the claim that the danger was from
the increasing cumulative amounts. Now, there can be no such claims.

As John pointed out above:

Dr. George Lucier, toxicologist and former director of the
Environmental
Toxicology Program, National Institute of Environmental Health Sciences
says, "Thimerosal contains organic mercury. Organic mercury is a known
developmental neurotoxin and the fetus and infants are at special risk.
Public health policies should not allow infants to be purposely
injected
with organic mercury."

Infants clear the mercury from Thimerosal incredibly fast. Further, at
the dose provided, there is no evidence of human toxicity.

Max.

"Mark Probert" wrote in message
...
Jan Drew wrote:
"Jeff" wrote in message
nk.net...
Ilena wrote in message
...
I've seen enormous amounts of Vaccination Disinformation posted on
Usenet ... interestingly enough for the most part by those connected
with the Quackwatch / Ratbags Posse headed by disgraced Peter Bowditch
of Genesse.

For sure ... disbarred Probert and such notable other anti-science
flacks will insult and defame Dr. Mercola ... such is their way.
Personally I find very little of what Mercola says is accurate or based
on science.

Mercury in Vaccines

Uproar over a little-known preservative, thimerosal, jostles U.S.
hepatitis B vaccination policy In 1997, when Frank Pallone, a
Democratic congressman from New Jersey, attached a simple amendment to
an FDA reauthorization bill, he could not have predicted that it would
cause such a commotion two years later. His amendment ran just 133
words. It gave FDA two years to "compile a list of drugs and foods
that contain intentionally introduced mercury compounds and . [to]
provide a quantitative and qualitative analysis of the mercury
compounds in the list.."

The bill later evolved into the landmark FDA Modernization Act of 1997
(FDAMA) and was signed into law on November 21, 1997. Pallone's
amendment undoubtedly sprang from his long interest in environmental
causes. But he had unwittingly set into motion a chain of events that
would, two years later, bring turmoil to the immunization policy world
and fears of harm to the nation's hepatitis B control effort.

Facts about thimerosal and mercury

Thimerosal is a water-soluble, cream-colored crystalline powder. It is
49.6% mercury by weight. In the human body, thimerosal is metabolized
to ethylmercury and thiosalicylate. The literature on thimerosal
metabolism and excretion is limited and old. Case reports have
demonstrated toxicity after massive overdoses. Toxicological
information on the chief metabolite of thimerosal, ethylmercury, is
extremely limited.

During the recent controversy over the safety of thimerosal in
vaccines, toxicologists have assumed that the toxicity of ethylmercury
is equivalent to the toxicity of methylmercury. The toxicity of
methylmercury is complex and depends on the type, level, and duration
of exposure. The primary environmental exposure is through consumption
of predator fish. A 6-ounce can of tuna fish contains an average of 17
micrograms of mercury.
This assumption is a bad assumption. Methylmercury is actively taken
into the brain; Ethylmercury is not. So the toxicity of ethylmercury is
a lot less.

http://www.altcorp.com/DentalInformation/exposure.htm
III. MECHANISMS, SOURCES & EPIDEMIOLOGY OF EXPOSURE
Sallie Bernard*, Albert Enayati, B.S., Ch.E., M.S.M.E., Heidi Roger,
Teresa Binstock, Lyn Redwood, R.N., M.S.N., C.R.N.P., Woody McGinnis,
M.D.


That is what Jeff said, very little science.

What YOU have said over and over and over. Jan Drew snips what she can not
handle.

What I have said proves to be the *TRUTH.*

You are famous for accusing other of your EXACTLY guilt.

You snipped the HUGH amount of science you can not handle.

Given that ethylmercury is equally neurotoxic as methylmercury (Magos et al,
1985), and that injected mercury is more harmful than ingested mercury (EPA,
1997, p.3-55; Diner and Brenner, 1998), the amount of injected ethylmercury
given to young children is cause for concern. The potential for Hg-induced
harm is compounded by the special vulnerability of infants (Gosselin et al,
1984). Mercury, which primarily affects the central nervous system, is most
toxic to the developing brain (Davis et al, 1994; Grandjean et al, 1999;
Yeates and Mortensen, 1994), and neonates exposed to methyl (organic)
mercury have been shown to accumulate significantly more Hg in the brain
relative to other tissues than do adults ( EPA, 1997, p.4-1). Mercury may
also be more likely to enter the infant brain because the blood-brain
barrier has not fully closed (Wild & Benzel, 1994). In addition, infants
under 6 months are unable to excrete mercury, most likely due to their
inability to produce bile, the main excretion route for organic mercury
(Koos and Longo, 1976; Clarkson, 1993). Bakir et al (1973) have shown that
those with the longest half-time of clearance are most likely to experience
adverse sequelae, while Aschner and Aschner (1990) have demonstrated that
the longer that organic mercury remains in neurons, the more it is converted
to its inorganic irreversibly-bound form, which has greater neurotoxicity.


ontact Dermatitis. 1993 Sep;29(3):152-4. Related Articles, Links


Ethylmercuric chloride: the responsible agent in thimerosal
hypersensitivity.


Pirker C, Moslinger T, Wantke F, Gotz M, Jarisch R.


Dermatologic and Pediatric Allergy Clinic, Vienna, Austria.


The causative agent of thimerosal allergy (sodium ethylmercury
thiosalicylate) has not previously been thoroughly investigated. To evaluate
whether the organic mercury component or the thiosalicylic acid molecule
induces thimerosal sensitization, 23 patients positive to thimerosal were
patch tested with ethylmercuric chloride, thiosalicylic acid and 8 different
derivatives of mercury. To date, ethylmercuric chloride has not been tested
in thimerosal allergy. 19/23 patients (82%) showed positive patch test
reactions to ethylmercuric chloride. 4/23 patients negative to ethylmercuric
chloride reacted positively to thimerosal 0.1% but not to thimerosal 0.05%.
8/23 patients (35%) also reacted to other mercurials. 20 controls negative
to thimerosal showed negative patch test reactions to ethylmercuric
chloride. Neither patients nor controls reacted to thiosalicylic acid. These
results indicate that testing with thimerosal 0.1% leads to false-positive
reactions and that the ethyl mercury component is the responsible agent in
thimerosal allergy.


PMID: 8222628 [PubMed - indexed for MEDLINE]


http://poisonevercure.150m.com/autism.htm


Autistic children are shown to retain abnormally high concentrations of
mercury from environmental sources such as vaccines.


********* (Until recently, the FDA administration concealed their knowledge
that thimerosal has been known to cross through the blood-brain barrier and
concentrate in the brain).***********


In a recent communication with Congressman Dr. Weldon, CDC conceded that
some of the routinely recommended vaccines contained the full amount of
thimerosal (25 mcg) as late as 2003. Those are not to expire until towards
the end of 2005. There is no existing reason to believe that manufactures
have it in mind to completely remove thimerosal from childhood vaccines in
the near future. Much to my alarm, documents recently obtained from the
World Health Organization (WHO)state that their policy is to lobby strongly
for maintaining thimerosal in vaccines as they see it necessary to use
childhood vaccines in third world countries. The mentality is that if
thimerosal is taken out of American childhood vaccines, the third world
countries will not accept thimerosal-containing childhood vaccines. This
seems to be a clear disturbing indication that, for whatever reason, WHO
desires to inoculate third world country populations with thimerosal
containing vaccines. This is an agency that claims to have an interest in
making sure that children in developing countries have the best
opportunities at life. How is that possible when they are being
deliberately poisoned with high concentrations of a neurotoxins?
There exists many decades worth of peer-reviewed literature (literally
hundreds) on the dangers of thimerosal which include case-reports, animal
studies, tissues culture studies, genetic studies, toxicology studies, and
biochemical studies. According to the above article, CDC, HHS and AAP warns
that 1/166 children have autistic spectrum disorders and even more alarming,
1/6 children have developmental and or behavioral disorders.
The World Health Organization's (WHO) Expert Committee on Biological
Standardization acknowledges that thimerosal is essential during vaccine
production to inactivate certain pathogenic organisms and toxins and prevent
microbial growth during vaccine storage and use. (click here to view
document). Read the Eli Lilly's, manufacturer of thimerosal, safety data
sheet on thimerosal. According to this document, thimerosal will react with
strong oxidizing agents and one listed is peroxides. Another vaccine
component. Also listed are the effects, including signs and symptoms of
exposure such as topical allergic dermatitis, topical hypersensitivity
reactions. Early signs of mercury poisoning are noted as nervous system
effects which include narrowing of the visual field and numbness in the
extremities. "Exposure to mercury in utero and in children can cause mild
to severe mental retardation and mild to severe motor coordination's
impairment". Primary routes of entry are listed as inhalation and skin
contact. For shipping information, there's no question of the label:
POISONS accompanied by the skull and bones picture label.
Mercury over stimulates the brain's immune system. Over stimulation of the
brain results in activation of the microglia widely dispersed in the brain.
When the microglia are activated, they release toxins killing surrounding
brains cells. Prolonged stimulation of the microglia by too many vaccines
kills far too many brain cells.
Though, some may find the reasoning of this imitation form of immunization
to make sense and logic, studying the peer review, lab work and studies
conducting the safety of such the practice will encourage you to think
twice. The dangers of inoculating children and adults with vile
microorganisms is potentially fatal. World Health Organization is privy to
this information. Other material indicate they know that more children
would die and or die quicker without the thimerosal. Sounds insane, but a
fact worth keeping in mind and or researching on your own. So, in order to
inactivate these microorganisms something even more toxic is needed to do
just that. That's where the thimerosal comes in. These facts alone should
raise a few eyebrows. Remember, in the records of mercury toxicology, it
only takes 35 mcg to kill a rabbit. Now, think about how much is in each
vaccine. There's 25mcg in Hib, Pneumococcal (except for Prevnar), DTaP, all
Tetanus brands. Then there's 12.5 in the Hep b. How much thimerosal is
needed should be your other indicator of the dangers of vaccines. The next
indicator is how many doses children receive by school registration.
It's one Russian roulette game after another to keep the big bucks packing
into the pockets of the big dogs.


Mol Psychiatry. 2004 Sep;9(9):833-45.Related Articles, Links


Neurotoxic effects of postnatal thimerosal are mouse strain dependent.


Hornig M, Chian D, Lipkin WI.


Jerome L and Dawn Greene Infectious Disease Laboratory, Department of
Epidemiology, Mailman School of Public Health, Columbia University, New
York, NY 10032, USA.


The developing brain is uniquely susceptible to the neurotoxic hazard posed
by mercurials. Host differences in maturation, metabolism, nutrition, sex,
and autoimmunity influence outcomes. How population-based variability
affects the safety of the ethylmercury-containing vaccine preservative,
thimerosal, is unknown. Reported increases in the prevalence of autism, a
highly heritable neuropsychiatric condition, are intensifying public focus
on environmental exposures such as thimerosal. Immune profiles and family
history in autism are frequently consistent with autoimmunity. We
hypothesized that autoimmune propensity influences outcomes in mice
following thimerosal challenges that mimic routine childhood immunizations.
Autoimmune disease-sensitive SJL/J mice showed growth delay; reduced
locomotion; exaggerated response to novelty; and densely packed,
hyperchromic hippocampal neurons with altered glutamate receptors and
transporters. Strains resistant to autoimmunity, C57BL/6J and BALB/cJ, were
not susceptible. These findings implicate genetic influences and provide a
model for investigating thimerosal-related neurotoxicity.


PMID: 15184908 [PubMed - indexed for MEDLINE]


1: Neurotoxicology. 1989 Winter;10(4):699-706.Related Articles, Links


Effect of organic and inorganic mercuric salts on Na+K+ATPase in different
cerebral fractions in control and intrauterine growth-retarded rats:
alterations induced by serotonin.


Chanez C, Flexor MA, Bourre JM.


Unite 26, INSERM, Hopital Fernand WIDAL, Paris, France.


An intrauterine growth-retarded (IUGR) model based on restriction of blood
supply to the rat fetus at the 17th day of pregnancy was studied. We
investigated in vitro the effects of thimerosal and mercuric chloride on
Na+K+ATPase activity in total brain homogenate, synaptosomes and myelin at
weaning. In addition, we evaluated the reversal effect of serotonin on
mercury-inhibited Na+K+ATPase activity. The toxicity, in terms of inhibition
of Na+K+ATPase activity was greater with mercuric chloride than with
thimerosal. Synaptosomes and principally myelin were more sensitive to the
metal salts than total homogenate. Serotonin stimulated the Na+K+ATPase
activity in total brain homogenate and synaptosomes but inhibited the enzyme
in the myelin fraction. This effect was more marked in the IUGR group than
in the control group. Serotonin (1 mM) added to total homogenate pretreated
with the mercury salts produced variable reversal effects. In the
synaptosomal fraction reverse effect was noted with serotonin. In myelin
fraction, added serotonin increased inhibition caused by thimerosal.


PMID: 2562765 [PubMed - indexed for MEDLINE]


1: Int J Biochem. 1983;15(1):5-7.Related Articles, Links


Rat brain (Na+-K+)ATPase: modulation of its ouabain-sensitive K+-PNPPase
activity by thimerosal.


Lewis RN, Bowler K.


1. The (Na+ + K+) ATPase activity of a rat brain synaptic membrane
preparation was inhibited by 10(-5) M thimerosal. 2. The ouabain inhibitable
K+-PNPPase activity of thimerosal treated membranes was compared with that
of untreated membranes with respect to sensitivity to temperature, ouabain,
K+ and ATP. 3. All those kinetic characteristics were substantially altered
by treatment with thimerosal.


PMID: 6298022 [PubMed - indexed for MEDLINE]


http://www.nupr.neu.edu/2-04/deth_article.pdf
Mol Psychiatry. 2004 Apr;9(4):358-70. Related Articles, Links


Activation of methionine synthase by insulin-like growth factor-1 and
dopamine: a target for neurodevelopmental toxins and thimerosal.


Waly M, Olteanu H, Banerjee R, Choi SW, Mason JB, Parker BS, Sukumar S,
Shim S, Sharma A, Benzecry JM, Power-Charnitsky VA, Deth RC.


Department of Pharmaceutical Sciences, Northeastern University, Boston,
MA 02115, USA.


Methylation events play a critical role in the ability of growth
factors to promote normal development. Neurodevelopmental toxins, such
as ethanol and heavy metals, interrupt growth factor signaling, raising
the possibility that they might exert adverse effects on methylation.
We found that insulin-like growth factor-1 (IGF-1)- and
dopamine-stimulated methionine synthase (MS) activity and
folate-dependent methylation of phospholipids in SH-SY5Y human
neuroblastoma cells, via a PI3-kinase- and MAP-kinase-dependent
mechanism. The stimulation of this pathway increased DNA methylation,
while its inhibition increased methylation-sensitive gene expression.
Ethanol potently interfered with IGF-1 activation of MS and blocked its
effect on DNA methylation, whereas it did not inhibit the effects of
dopamine. Metal ions potently affected IGF-1 and dopamine-stimulated MS
activity, as well as folate-dependent phospholipid methylation: Cu(2+)
promoted enzyme activity and methylation, while Cu(+), Pb(2+), Hg(2+)
and Al(3+) were inhibitory. The ethylmercury-containing preservative
thimerosal inhibited both IGF-1- and dopamine-stimulated methylation
with an IC(50) of 1 nM and eliminated MS activity. Our findings outline
a novel growth factor signaling pathway that regulates MS activity and
thereby modulates methylation reactions, including DNA methylation. The
potent inhibition of this pathway by ethanol, lead, mercury, aluminum
and thimerosal suggests that it may be an important target of
neurodevelopmental toxins.


PMID: 14745455 [PubMed - in process]


Blood work from kids SHOULD have been taken within two to four hours, NOT
days
after vaccines, thimerosal crosses the blood brain barrier and is stored in
the
brain.


http://www.altcorp.com/DentalInformation/asdexperts.htm



A pediatric dose of hepatitis B vaccine contains 12.5 micrograms. The
major toxicity of mercury is manifested in the central nervous system.


Except that ethylmercury, in the doses used, has never been shown to be
harmful the human brain.



http://health.groups.yahoo.com/group...ccinethensick/

http://www.nccn.net/~wwithin/hepatitisB.htm


http://www.mercola.com/2002/jan/23/h...is_vaccine.htm


Is Hepatitis Vaccine Safe?


The Vaccine Adverse Event Reporting System (VAERS) was developed by the
government to report vaccine reactions. Many experts believe that only 10%
of the adverse reactions are reported though as reporting is not mandated by
law.


Even with only 10% of the problems being reported there were nearly 25,000
VAERS hepatitis B reports from July 1990 to October 31, 1998, showing 439
deaths and 9673 serious reactions involving emergency room visits,
hospitalization, disablement or death.


The presence of findings such as brain edema in healthy infants who die very
soon after receiving hepatitis B vaccine is profoundly disturbing,
especially in view of the frequency of neurologic symptoms in the VAERS.


Does this make any sense?


Is Hepatitis B Vaccine Effective in Newborns?


Vaccine derived immunity is thought to be short lived. Between 30-50% of
vaccinated individuals lose their antibiodies within 7 years.


Up to 60% of persons who initially respond will lose detectable antibodies
within 12 years.. So that means that these vaccines will provide little to
no protection to the real risks of acquiring hepatitis B, promiscuous sexual
behavior and IV drug abuse.


Does this make any sense?


How Many Children Are Hurt or Helped By Hepatitis B Vaccine?


Hepatitis B is a rare, mainly blood-transmitted disease. In 1996 only 54
cases of the disease were reported to the CDC in the 0-1 age group. There
were 3.9 million births that year, so the observed incidence of hepatitis B
in the 0-1 age group was just 0.001%. In the Vaccine Adverse Event Reporting
System (VAERS), there were 1,080 total reports of adverse reactions from
hepatitis B vaccine in 1996 in the 0-1 age group, with 47 deaths reported.


Jeff is much like you..he gives those *organized medicine* pat answer
replies and

prefers to remain ignorant of REAL science and REAL adverse effects.

Mark Probert wrote:
Recently, Shattuck showed that there may be no evidence that the autism
rates actually went up. Of course, the anti-vac liars immediately
trashed him, as they have a vested interest in the so-called autism
epidemic.

That's true, but we like to call them "children" instead of "vested
interests."

Then again, maybe there is no connection at all. There
has been no large scale study to prove one way or another. That's all
beside the point. My reason for posting is to address the fact that
infants could still be getting thimerosal in their vaccine schedule.

Like I said, one shot. Period. It was the claim that the danger was from
the increasing cumulative amounts. Now, there can be no such claims.

.... for thimerosal. I agree... as long as it's 100% out of the
picture. That does not eliminate claims for aluminum, eggs proteins,
gelatin, DNA from other animals or any of the other potentially
dangerous ingredients.

This weekend I stumbled upon a new concern for vaccines of which I had
no previous knowledge. I have reason to believe that my 8 month old
may have a gelatin allergy, or at least a sensitivity. I wanted to
learn more about it so I googled "gelatin allergy." To my surprise,
most of the web sites google returned were discussing vaccines. The
gelatin in some vaccines has proven very hazardous for a small number
of people. Upon reading more, there are apparently causes for concern
over egg proteins, sorbitol, and neomycin as well... all commonly found
in many vaccines. Here's one of the links I found:

http://www.jcaai.org/pp/anaph_10_avian.asp

The link talks about "skin testing" to determine if the
would-be-recipient will be allergic to the ingredients, but this is new
to me, so I don't know that much about it. I don't recall "skin tests"
being SOP for giving vaccines. Is it?

As John pointed out above:

Dr. George Lucier, toxicologist and former director of the
Environmental
Toxicology Program, National Institute of Environmental Health Sciences
says, "Thimerosal contains organic mercury. Organic mercury is a known
developmental neurotoxin and the fetus and infants are at special risk.
Public health policies should not allow infants to be purposely
injected
with organic mercury."

Infants clear the mercury from Thimerosal incredibly fast. Further, at
the dose provided, there is no evidence of human toxicity.

I don't consider a half life of 24.2 days of mercury being in the brain
"incredibly fast"... especially when we're talking about a length of
time that may make up a very large percentage of the time the infant
has been alive.

http://www.pubmedcentral.nih.gov/art...?artid=1280369
"Brain concentrations of total mercury were approximately 3-4 times
lower in the thimerosal group than in the methylmercury group, and
total mercury cleared more rapidly in the thimerosal group (with a
half-life of 24.2 days versus 59.5 days). However, the proportion of
inorganic mercury in the brain was much higher in the thimerosal group
(21-86% of total mercury) compared to the methylmercury group
(6-10%). Brain concentrations of inorganic mercury were approximately
twice as high in the thimerosal group compared to the methylmercury
group. Inorganic mercury remains in the brain much longer than organic
mercury, with an estimated half-life of more than a year. It's not
currently known whether inorganic mercury presents any risk to the
developing brain."

But we've both discussed this before. We didn't see eye to eye then,
and I don't imagine we'll come to an agreement this time either. The
fact is, the data does not exist. In my opinion, if you're a parent
that knows how to use nutrition to protect your children, it's best to
err on the side of caution and avoid unnecessary vaccination shots.
(Note that I did NOT say "Avoid vaccination.") If you're a parent
that feeds your children whatever is convenient or the easiest to
prepare, get your kids vaccinated.

Max.

"Mark Probert" wrote in message
...
Max C. wrote:
Mark Probert wrote:
Max C. wrote:
Mark Probert wrote:
Mercury in Vaccines
What vaccines? It has been removed! This is like complaining about
Nixon
being president.
That's only partially correct. Thimerosal is still in flu shots.
http://www.cdc.gov/flu/about/qa/thimerosal.htm

And flu shots are now recommended for infants.
http://www.prnewswire.com/cgi-bin/st...02163256&EDATE

But the anti-vac liars used to whinny and whine that it was the
cumulative effects of all those shots that caused the "autism epidemic"
and not just a single shot.

There is some evidence that autism rates are going down, but it has
been disputed.

The reason that it is disputed is that the "evidence" datasets used are
not designed to make such evaluations. Thus, there is no evidence that the
autism rates are going down.

Recently, Shattuck showed that there may be no evidence that the autism
rates actually went up. Of course, the anti-vac liars immediately trashed
him, as they have a vested interest in the so-called autism epidemic.

Then again, maybe there is no connection at all. There
has been no large scale study to prove one way or another. That's all
beside the point. My reason for posting is to address the fact that
infants could still be getting thimerosal in their vaccine schedule.

Like I said, one shot. Period. It was the claim that the danger was from
the increasing cumulative amounts. Now, there can be no such claims.

As John pointed out above:

Dr. George Lucier, toxicologist and former director of the
Environmental
Toxicology Program, National Institute of Environmental Health Sciences
says, "Thimerosal contains organic mercury. Organic mercury is a known
developmental neurotoxin and the fetus and infants are at special risk.
Public health policies should not allow infants to be purposely
injected
with organic mercury."

Infants clear the mercury from Thimerosal incredibly fast. Further, at the
dose provided, there is no evidence of human toxicity.

Blood work from kids SHOULD have been taken within two to four hours, NOT
days
after vaccines, thimerosal crosses the blood brain barrier and is stored in
the
brain.


Max.