Acute Encephalopathy Followed by Permanent Brain Injury or Death Associated With Further Attenuated Measles Vaccines

"A total of 48 children, ages 10 to 49 months, met the inclusion criteria
after receiving measles vaccine, alone or in combination. Eight children
died, and the remainder had mental regression and retardation, chronic
seizures, motor and sensory deficits, and movement disorders. "

http://pediatrics.aappublications.or...ract/101/3/383

PEDIATRICS Vol. 101 No. 3 March 1998, pp. 383-387


Acute Encephalopathy Followed by Permanent Brain Injury or Death Associated
With Further Attenuated Measles Vaccines: A Review of Claims Submitted to
the National Vaccine Injury Compensation Program
Received Jul 30, 1997; accepted Sep 23, 1997.

Robert E. Weibel*, Vito Caserta*, David E. Benor , and Geoffrey Evans*

From the * Division of Vaccine Injury Compensation, National Vaccine Injury
Compensation Program, Health Resources and Services Administration, Public
Health Service, Rockville, Maryland; and the Office of the General Counsel,
United States Department of Health and Human Services, Rockville, Maryland.

Objective. To determine if there is evidence for a causal relationship
between acute encephalopathy followed by permanent brain injury or death
associated with the administration of further attenuated measles vaccines
(Attenuvax or Lirugen, Hoechst Marion Roussel, Kansas City, MO), mumps
vaccine (Mumpsvax, Merck and Co, Inc, West Point, PA), or rubella vaccines
(Meruvax or Meruvax II, Merck and Co, Inc, West Point, PA), combined measles
and rubella vaccine (M-R-Vax or M-R-Vax II, Merck and Co, Inc, West Point,
PA), or combined measles, mumps, and rubella vaccine (M-M-R or M-M-R II,
Merck and Co, Inc, West Point, PA), the lead author reviewed claims
submitted to the National Vaccine Injury Compensation Program.

Methods. The medical records of children who met the inclusion criteria of
receiving the first dose of these vaccines between 1970 and 1993 and who
developed such an encephalopathy with no determined cause within 15 days
were identified and analyzed.

Results. A total of 48 children, ages 10 to 49 months, met the inclusion
criteria after receiving measles vaccine, alone or in combination. Eight
children died, and the remainder had mental regression and retardation,
chronic seizures, motor and sensory deficits, and movement disorders. The
onset of neurologic signs or symptoms occurred with a nonrandom,
statistically significant distribution of cases on days 8 and 9. No cases
were identified after the administration of monovalent mumps or rubella
vaccine.

Conclusions. This clustering suggests that a causal relationship between
measles vaccine and encephalopathy may exist as a rare complication of
measles immunization.
Key words: measles vaccine, encephalopathy, encephalitis.

"john" wrote in message
...
"A total of 48 children, ages 10 to 49 months, met the inclusion
criteria after receiving measles vaccine, alone or in combination.
Eight children died, and the remainder had mental regression and
retardation, chronic seizures, motor and sensory deficits, and
movement disorders. "

http://pediatrics.aappublications.or...ract/101/3/383

PEDIATRICS Vol. 101 No. 3 March 1998, pp. 383-387


Hypocrite! If what was written here were true, then this was in 1998 way
before Wakefield was given a kick in the pants. He advocated single
measles vaccine, always had, yet here you are posting crap that opposes
all you stood for these last few months.

You Suh are a total fraud, a hypocrite, and fearmonger!

How many children must die, due to your postings, before you recant?

From: Teresa Binstock
QUESTIONS? COINCIDENCE??:
Ironic that the Weibel et al Feb-1998 paper's final stages and its
peer-review process were occurring at the same time as Wakefield et al
Mar-1998 was being finalized for publication in Lancet.

Perusing the paper suggests MMR's role in everything from tics to PDD to
autism. Might Tylenol etc have diminished adverse effects (eg, prevented
death and most comas) while allowing MMR-induced encephalopathies to
manifest differently - eg, as autism?

Exclusion: In 1995, policy regarding dates for onset of vaccine-related
encephalopathy changed from 15 days to between 5 and 15 days, yet Weibel et
al found that ~16% of the cases had onset on day 4 or less. Also, rhetoric
in Weibel et al may be somewhat ambiguous in regard to counting occurrences
in days 1 thru 4 or in days 1 thru 5. Regardless, official policy to exclude
MMR-related encephalopathies in days 1-4 augments under-reporting Weibel et
al presume to have occurred given requirements of the compensation program.

Question after perusing the paper, the researchers excluded postictal
phenomena, but I can't help but wonder: in how many kids who received the
MMR and developed high fever with non-mild seizures, how many such kids had
measurable deteriorations that occurred postictally?


I had hoped to ask Dr. Weibel the question about the possibility of
postictal deteriorations having been excluded.

Pubmed indicated that Weibel RE's last published study was the 1998 gem that
reported MMR damage. A google search showed that he still participated as
part of an HHS department at least as recently as 2006.

Teresa