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Breast-feeding may lower blood pressure in childhood
www.reuters.com, Health eLine, 3/1/04
Breast-feeding may lower blood pressure in childhood Last Updated: 2004-03-01 16:43:42 -0400 (Reuters Health) NEW YORK (Reuters Health) - It has been reported that individuals who were breast-fed during infancy appear to have decreased risk of death from heart disease. Now, new research suggests that this may be due to blood pressure-lowering effects of breast-feeding. "The wider promotion of breast-feeding is a potential component of the public health strategy to reduce population levels of blood pressure," the researchers suggest in the current issue of Circulation: Journal of the American Heart Association. The findings are based on a study of 4,763 non-twin, full-term infants who had their blood pressures determined at 7.5 years of age. Questionnaires were also sent to the mothers to assess breast-feeding during infancy. Dr. Richard M. Martin, from the University of Bristol in the UK, and colleagues found that breast-fed children had systolic blood pressure--the top number of the blood pressure reading--1.2 mm Hg lower than those of children who were not breast-fed. The corresponding decrease for diastolic pressure--the lower number of the blood pressure reading--was 0.9 mm Hg After Martin's group took into consideration various demographic factors that could contribute to the development of high blood pressure, the effects of breast-feeding were lessened, although still statistically significant. The findings did not differ between infants who were breast-fed only and those who received a combination of breast milk and formula, the authors note. However, the duration of breast-feeding did have an effect; for each three-month period of feeding, the systolic pressure fell by 0.2 mm Hg. Although breast-feeding was only linked to a small reduction in blood pressure, this could still have a strong impact on heart disease mortality, Martin said in a statement. "A one-percent reduction in population systolic blood pressure levels is associated with about a 1.5-percent reduction in all-cause mortality, equivalent to a lessening in premature death of about 8000 to 2000 deaths per year in the United States and the United Kingdom, respectively," he added. SOURCE: Circulation, March 1, 2004. |
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Breast-feeding may lower blood pressure in childhood
"JG" wrote in message ...
www.reuters.com, Health eLine, 3/1/04 Breast-feeding may lower blood pressure in childhood Last Updated: 2004-03-01 16:43:42 -0400 (Reuters Health) NEW YORK (Reuters Health) - It has been reported that individuals who were breast-fed during infancy appear to have decreased risk of death from heart disease. Now, new research suggests that this may be due to blood pressure-lowering effects of breast-feeding. "The wider promotion of breast-feeding is a potential component of the public health strategy to reduce population levels of blood pressure," the researchers suggest in the current issue of Circulation: Journal of the American Heart Association. The findings are based on a study of 4,763 non-twin, full-term infants who had their blood pressures determined at 7.5 years of age. Questionnaires were also sent to the mothers to assess breast-feeding during infancy. Dr. Richard M. Martin, from the University of Bristol in the UK, and colleagues found that breast-fed children had systolic blood pressure--the top number of the blood pressure reading--1.2 mm Hg lower than those of children who were not breast-fed. The corresponding decrease for diastolic pressure--the lower number of the blood pressure reading--was 0.9 mm Hg After Martin's group took into consideration various demographic factors that could contribute to the development of high blood pressure, the effects of breast-feeding were lessened, although still statistically significant. The findings did not differ between infants who were breast-fed only and those who received a combination of breast milk and formula, the authors note. However, the duration of breast-feeding did have an effect; for each three-month period of feeding, the systolic pressure fell by 0.2 mm Hg. Although breast-feeding was only linked to a small reduction in blood pressure, this could still have a strong impact on heart disease mortality, Martin said in a statement. "A one-percent reduction in population systolic blood pressure levels is associated with about a 1.5-percent reduction in all-cause mortality, equivalent to a lessening in premature death of about 8000 to 2000 deaths per year in the United States and the United Kingdom, respectively," he added. SOURCE: Circulation, March 1, 2004. Not to belabor a point - but another example of the lay press not quite getting it right. First, its Circulation, March 2, not March 1. Here's an interesting piece of data - "Breast feeding was inversely associated with maternal and child BMI." In case you missed the implication - the non-breastfead kids - you know, the ones with the higher BP - where chunkier than those with lower BP (the breastfed group). Oh, and the breastfed cohort was taller (even if the text says the opposite, the table is correct) and had a lower resting pulse rate. These results have p values that are in the .01 to .0001 range. The regression equation appears to be a purposeful forward stepwise with BF/NBF as the first variable. The child BMI adds significant explanatory power over and above the BF/BFN - this to me suggests that the BF/BNF variable isn't the best predictor of outcome, in spite of the non-significant interaction term. I think, in reading the study report itself, that the effect (about 1mmHg) and all the confounders, the conclusions in the news report are hardly accurate. "Now, new research suggests that this [long-term mortality benefit of lowered BP] may be due to blood pressure-lowering effects of breast-feeding." This is bull. The authors, in the study, are VERY clear in their conclusions that there is NO causality evidence. They are VERY clear that the assumption of causality is an assumption and is NOT supported by the data. They are also very very clear that though their experience and the literature appears to suggest that lower BP in kids translates to a long term lower BP in adults, these data hardly have this power. The authors provide a scenario of hypotheses based on a series of assumptions that suggest that there MAY be a link between breast feeding and some long term mortality benefit. Reuters says something a bit different. In fact, Reuters uses the UNADJUSTED parameter estimates in their report - not the appropriate adjusted results of 0.8 and 0.6 (with some ratehr big confidence intervals, btw). It's not like these numbers weren't CLEARLY spelled out in the ABSTRACT - they didn't even need to read the article to get this information. And if this type of journalistic sloppiness isn't problematic for you, you aren't much of a critical thinker. js |
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