Deadly side-effects earn ADHD drugs warning

Saturday » May 27 » 2006

Deadly side-effects earn ADHD drugs warning

Sharon Kirkey
CanWest News Service
http://www.canada.com/topics/news/na...53c8cb&k=97407

Saturday, May 27, 2006


Health Canada has issued new warnings of rare heart risks for all
drugs used for attention deficit hyperactivity disorder, including a
risk of sudden death.

A public advisory issued Friday cautions that any child or adult with
high blood pressure, heart disease or heart abnormalities, hardening
of the arteries or an overactive thyroid gland should not use Ritalin
or seven other ADHD medications.

The pills - among the most widely prescribed drugs to Canadian
children - increase heart rate and blood pressure.

''The effects are usually mild or moderate, but in some patients, this
stimulation may - in rare cases - result in cardiac arrests, strokes
or sudden death,'' Health Canada warns.

The agency has strengthened the safety labels and prescribing
information for Adderall XR, Concerta, Dexedrine, Ritalin and Ritalin
SR and Strattera, as well as Attenade and Biphentin, two drugs that
have been approved but are not yet available in Canada.

More than 1.9 million prescriptions for the stimulants were filled by
Canadian retail drugstores in the 12 months ending April 30, 2006,
according to health research firm IMS Health. An estimated three
million U.S. children, and 1.5 million adults, are on
psycho-stimulants.

American drug regulators are considering adding a ''black box'' - the
most serious warning it can issue - to ADHD drugs, warning of rare
heart-related risks. There have been 25 reports in the U.S. of
children and adults who died suddenly between 1999 and 2003 after
taking one of the drugs, including a 13-year-old boy who died within
one hour of receiving his first dose. An autopsy revealed he had a
genetic heart disorder.

No deaths have been reported in Canada.

''The warning has gone out because of a theoretical increased risk of
these events happening,'' says Dr. Supriya Sharma, associate
director-general of Health Canada's therapeutic products directorate.
The risks of cardiac arrests, strokes or sudden death occur in less
than one in 10,000 patients, she says.

In a "Dear health care professional" letter issued Friday, doctors are
being advised to start the drugs at the lowest possible dose and to
increase it slowly. ''It's, 'start low, go slow,''' Sharma says.

Before starting the drugs, patients should tell their doctor if they
are involved in strenuous exercise or activities, are using other
drugs for ADHD or have a family history of sudden cardiac death.

No one should stop taking their medication without first speaking with
a doctor, Sharma says.

''These drugs also give benefit to people as well. We don't want
people to be going unnecessarily off the medications if there are
benefits.

''(These are) still very rare side effects, this is a precautionary
measureE.we don't want people to be panicking.''

ADHD is one of the most commonly diagnosed neurological disorders in
school-aged children.

Dr. Atilla Turgay, a psychiatrist and chief of medical staff at
Ontario's Scarborough Hospital, said the new warnings are appropriate.
But he worries they could make parents more hesitant to use the drugs.

''There would be many patients whose education, social life and
quality of family life would be so much disturbed if they are not on
medication.

''I remember two cases where the parents were about to give the child
up to the local Children's Aid Society because of unmanageable
behaviour.'' Untreated ADHD can lead to aggressive behaviour and drug
abuse later in life.

''We really have to judge very carefully the risk of not treating
ADHD," Turgay says.

But Dr. Steven Nissen, of the Cleveland Clinic, says the warnings
about serious cardiovascular risks with ADHD drugs ''might slow the
exponential growth in the use of amphetamines and similar stimulants,"
which he says has reached "epidemic proportions."

Writing in this week's New England Journal of Medicine, Nissen says
nearly 10 per cent of pre-adolescent boys in the U.S. are taking the
drugs.



© CanWest News Service 2006





*** Posted via a free Usenet account from http://www.teranews.com ***

The research into ADHD has shown that most children's diet has an
adverse effect on their ability to concentrate and learn. There are
also psychological issues that are sometimes involved. These stem from
the socio-economic environment at school and home. Harsh medication is
not the answer to these problems. Don't believe the first word you
hear either. Research and make your decision when you have compiled a
vast amount of data. www.shaklee.net/waltongates

Rick wrote:
The research into ADHD has shown that most children's diet has an
adverse effect on their ability to concentrate and learn.

Actually, the research into AD/HD shows that AD/HD has nothing to do
with diet. In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.

You can visit the website of the AAP and learn for yourself.

There are
also psychological issues that are sometimes involved. These stem from
the socio-economic environment at school and home.

If there are psychological issues, then the proper diagnosis should
address them. They are NOT the basis for a proper AD/HD diagnosis.

Harsh medication is
not the answer to these problems.

True. Neither is a supplement. Addressing the psychological issues at
home and in school is important.

Don't believe the first word you
hear either.

Good advice for analyzing your post.

Research and make your decision when you have compiled a
vast amount of data. www.shaklee.net/waltongates

You would not be selling something, would you?

"Mark Probert" wrote in message
...
Rick wrote:
The research into ADHD has shown that most children's diet has an
adverse effect on their ability to concentrate and learn.

Actually, the research into AD/HD shows that AD/HD has nothing to do with
diet.

Blatant repeated lie!

http://tinyurl.com/b2r6l

Foods and additives are common causes of the attention deficit hyperactive
disorder in children.


Boris M, Mandel FS.


North Shore Hospital-Cornell Medical Center, Manhasset, New York.


The attention deficit hyperactive disorder (ADHD) is a neurophysiologic
problem that is detrimental to children and their parents. Despite previous
studies on the role of foods, preservatives and artificial colorings in ADHD
this issue remains controversial. This investigation evaluated 26 children
who meet the criteria for ADHD. Treatment with a multiple item elimination
diet showed 19 children (73%) responded favorably, P .001. On open
challenge, all 19 children reacted to many foods, dyes, and/or
preservatives. A double-blind placebo controlled food challenge (DBPCFC) was
completed in 16 children. There was a significant improvement on placebo
days compared with challenge days (P = .003). Atopic children with ADHD had
a significantly higher response rate than the nonatopic group. This study
demonstrates a beneficial effect of eliminating reactive foods and
artificial colors in children with ADHD. Dietary factors may play a
significant role in the etiology of the majority of children with ADHD.


http://tinyurl.com/c2lez


The role of diet and behaviour in childhood.


Breakey J.


This short review summarizes the most important research, particularly that
from 1985 to 1995, on the relationship between diet and behaviour. Relevant
studies particularly those using double-blind placebo controlled food
challenge methodology were selected, and are presented within a historical
context. Summary tables of the early development of concepts and later
pertinent studies are provided. The research has shown that diet definitely
affects some children. Rather than becoming simpler the issue has become
demonstrably more complex. The range of suspect food items has broadened,
and some non-food items are relevant. Symptoms which may change include
those seen in attention deficit disorder (ADD) and attention deficit
hyperactivity disorder (ADHD), sleep problems and physical symptoms, with
later research emphasizing particularly changes in mood. The reports also
show the range of individual differences both in the food substances
producing reactions and in the areas of change.


http://tinyurl.com/cke6f


Controlled trial of cumulative behavioural effects of a common bread
preservative.


Dengate S, Ruben A.





OBJECTIVE: Many anecdotes and one scientific report describe cumulative
behavioural effects of bread preservative on children. METHODOLOGY:
Twenty-seven children, whose behaviour improved significantly on the Royal
Prince Alfred Hospital diet, which excludes food additives, natural
salicylates, amines and glutamates, were challenged with calcium propionate
(preservative code 282) or placebo through daily bread in a double-blind
placebo-controlled crossover trial. RESULTS: Due to four placebo responders,
there was no significant difference by ANOVA of weighted placebo and
challenge Rowe Behaviour Rating Inventory means, but a statistically
significant difference existed in the proportion of children whose
behaviours 'worsened' with challenge (52%), compared to the proportion whose
behaviour 'improved' with challenge (19%), relative to placebo (95%
confidence intervals 14-60%). CONCLUSIONS: Irritability, restlessness,
inattention and sleep disturbance in some children may be caused by a
preservative in healthy foods consumed daily. Minimizing the concentrations
added to processed foods would reduce adverse reactions. Testing for
behavioural toxicity should be included in food additive safety evaluation.


http://openpr.com/drucken/?id=1661

http://www.upi.com/ConsumerHealthDai...=20060316-0911...

Ped Med: The skinny on ADHD contributors
By LIDIA WASOWICZ
UPI Senior Science Writer


SAN FRANCISCO, March 17 (UPI) -- Nutritionists are convinced that, just like
everyone else, children with attention-deficit/hyperactivity disorder are
what they eat.


Specifically, the specialists have their eye on so-called omega-3 fatty
acids as playing some role in the condition that, in general, is marked by
trouble keeping still, difficulty in maintaining attention, propensity
toward acting impulsively or some combination of the three.


Omega-3 fatty acids are plentiful in cold-water fish, such as salmon,
herring, tuna, clams, crab, cod, flounder, sole, halibut, catfish, trout and
shrimp. They also abound in nuts; soybeans; walnut, olive and flaxseed oil;
seeds; whole grains and dark leafy greens.


The fatty acids comprise a hefty component of the brain, which weighs in at
about 60-percent fat.


The compounds, which studies indicate are essential for forming and
maintaining the dopamine system, have been found in short supply in some,
though not all, children diagnosed with ADHD.


Many researchers see ADHD as a hereditary imbalance of brain chemicals, such
as dopamine -- which regulates movement, emotion, motivation and sensations
of pleasure.


That view is strongly contested by critics who point to a dearth of physical
evidence for such a notion.


Whatever their connection to the "feel-good" chemical in the brain, the
omega-3 fatty acids appear to have an impact on a child's behavior,
portending problems in youngsters who don't have enough of the compounds.


As one example, a recent Duke University study of 96 boys ages 6 to 12
indicated those with low blood levels of omega-3 fatty acids face increased
risk of ADHD-like behavior, learning and health challenges.


There is also some evidence the compounds may play a benevolent role in the
production of myelin, a protective insulation that coats the brain's
internal wiring,


A novel model of human brain development and degeneration proposed by
researchers at the University of California, Los Angeles implicates
disruption of myelin production in such childhood developmental disorders as
autism and ADHD.


From a review of scanned and autopsied brain tissue, the investigators
unraveled the role of myelin in these conditions.


Laden with more cholesterol than any other brain component, the sheet of fat
surrounds the spindly nerve-cell extensions called axons, permitting them to
carry messages to their neighbors in the safety and security of their armor.


The thicker and heavier the cells' coat, the faster and more effective their
communication, said team leader Dr. George Bartzokis, professor of neurology
at the David Geffen School of Medicine and director of the UCLA Memory
Disorders and Alzheimer's Disease Clinic and the Clinical Core of the UCLA
Alzheimer's Disease Research Center.


The pioneering neuroscientist discovered that myelin production continues
unabated throughout the first four decades of life before peaking and
plummeting at age 45. His latest research portrays the protective shield as
the neural system's Achilles' heel, vulnerable to a host of environmental
assaults.


"Myelination, a process uniquely elaborated in humans, arguably is the most
important and most vulnerable process of brain development as we mature and
age," Bartzokis said.


Without adequate insulation, cells won't connect properly, he has found in a
series of experiments that showed a breakdown in the sheath can expose the
naked wiring beneath and open the gates to an array of neurological and
behavioral problems.


Bartzokis's theory holds that humans "myelinate" different circuits at
various points in life, which could explain the sizeable differences between
brain diseases of the young and old.


An early disruption of the process, for instance, may throw for a loop the
development of the basic circuits that govern language and social
communication, two key impairments in autism.


A glitch during the early school years could hamper the ability to process
information efficiently and effectively, leading to deficits in attention
that characterize ADHD. Later in life, the result of a malfunction could be
Alzheimer's disease.


To Bartzokis, the human brain is akin to high-speed Internet.


"The speed, quality and bandwidth of the connections determine the brain's
ability to process information, and all these depend in large part on the
insulation that coats the brain's connecting wires," he said.


The findings may explain why developmental disorders leave no calling card
in the brain. "There's no dead anything on autopsy," Bartzokis said. "Those
brain connections just never developed normally."


Bartzokis's studies also show female brains make better myelin, which could
explain why boys are at much greater risk for autism, ADHD and other
problems.


"On the positive side, there are some interesting things to consider,"
Bartzokis said. "For example, essential fatty acids are fats that are
necessary for membrane production, and myelin is essentially pure membrane."


"They are called 'essential' because the human body cannot produce them,
and, therefore, they are like 'vitamins' -- they need to come from a good
diet," he added. "Thus, nutrition is very important because the brain is
very busy trying to build the myelin sheaths."


Still, researchers don't have the skinny on the exact relationship between
the fats and ADHD.


Although alternative medicine practitioners report some success in
ameliorating symptoms with the use of fatty acid, mineral, vitamin B and
other supplements, none of these has been embraced as standard therapy.


Conventional and complementary practices also part ways on the role, and
remedial potential, of food additives, sugar or allergens. All of these
remain controversial, having failed to withstand rigorous scientific
scrutiny, according to a compilation of ADHD data by Dr. Peter Jensen,
director of the Center for the Advancement of Children's Mental Health at
Columbia University.


Next: Seeking environmental clues to ADHD.


(Editors' Note: This series on ADHD is based on a review of hundreds of
reports and a survey of more than 200 specialists.)




In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.

You can visit the website of the AAP and learn for yourself.

There are
also psychological issues that are sometimes involved. These stem from
the socio-economic environment at school and home.

If there are psychological issues, then the proper diagnosis should
address them. They are NOT the basis for a proper AD/HD diagnosis.

Harsh medication is
not the answer to these problems.

True. Neither is a supplement. Addressing the psychological issues at home
and in school is important.

Don't believe the first word you
hear either.

Good advice for analyzing your post.

Research and make your decision when you have compiled a
vast amount of data. www.shaklee.net/waltongates

You would not be selling something, would you?

Jan Drew wrote:
"Mark Probert" wrote in message
...
Rick wrote:
The research into ADHD has shown that most children's diet has an
adverse effect on their ability to concentrate and learn.

Actually, the research into AD/HD shows that AD/HD has nothing to do with
diet.

Blatant repeated lie!

Still refusing to learn, Jan? Still accusing other's of lying when they
disagree with you? How christian.

Do you have any reply to the relevant part of Mark's post:

"In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.

You can visit the website of the AAP and learn for yourself."

No?

Cathy


http://tinyurl.com/b2r6l

Foods and additives are common causes of the attention deficit hyperactive
disorder in children.


Boris M, Mandel FS.


North Shore Hospital-Cornell Medical Center, Manhasset, New York.


The attention deficit hyperactive disorder (ADHD) is a neurophysiologic
problem that is detrimental to children and their parents. Despite previous
studies on the role of foods, preservatives and artificial colorings in ADHD
this issue remains controversial. This investigation evaluated 26 children
who meet the criteria for ADHD. Treatment with a multiple item elimination
diet showed 19 children (73%) responded favorably, P .001. On open
challenge, all 19 children reacted to many foods, dyes, and/or
preservatives. A double-blind placebo controlled food challenge (DBPCFC) was
completed in 16 children. There was a significant improvement on placebo
days compared with challenge days (P = .003). Atopic children with ADHD had
a significantly higher response rate than the nonatopic group. This study
demonstrates a beneficial effect of eliminating reactive foods and
artificial colors in children with ADHD. Dietary factors may play a
significant role in the etiology of the majority of children with ADHD.


http://tinyurl.com/c2lez


The role of diet and behaviour in childhood.


Breakey J.


This short review summarizes the most important research, particularly that
from 1985 to 1995, on the relationship between diet and behaviour. Relevant
studies particularly those using double-blind placebo controlled food
challenge methodology were selected, and are presented within a historical
context. Summary tables of the early development of concepts and later
pertinent studies are provided. The research has shown that diet definitely
affects some children. Rather than becoming simpler the issue has become
demonstrably more complex. The range of suspect food items has broadened,
and some non-food items are relevant. Symptoms which may change include
those seen in attention deficit disorder (ADD) and attention deficit
hyperactivity disorder (ADHD), sleep problems and physical symptoms, with
later research emphasizing particularly changes in mood. The reports also
show the range of individual differences both in the food substances
producing reactions and in the areas of change.


http://tinyurl.com/cke6f


Controlled trial of cumulative behavioural effects of a common bread
preservative.


Dengate S, Ruben A.





OBJECTIVE: Many anecdotes and one scientific report describe cumulative
behavioural effects of bread preservative on children. METHODOLOGY:
Twenty-seven children, whose behaviour improved significantly on the Royal
Prince Alfred Hospital diet, which excludes food additives, natural
salicylates, amines and glutamates, were challenged with calcium propionate
(preservative code 282) or placebo through daily bread in a double-blind
placebo-controlled crossover trial. RESULTS: Due to four placebo responders,
there was no significant difference by ANOVA of weighted placebo and
challenge Rowe Behaviour Rating Inventory means, but a statistically
significant difference existed in the proportion of children whose
behaviours 'worsened' with challenge (52%), compared to the proportion whose
behaviour 'improved' with challenge (19%), relative to placebo (95%
confidence intervals 14-60%). CONCLUSIONS: Irritability, restlessness,
inattention and sleep disturbance in some children may be caused by a
preservative in healthy foods consumed daily. Minimizing the concentrations
added to processed foods would reduce adverse reactions. Testing for
behavioural toxicity should be included in food additive safety evaluation.


http://openpr.com/drucken/?id=1661

http://www.upi.com/ConsumerHealthDai...=20060316-0911...

Ped Med: The skinny on ADHD contributors
By LIDIA WASOWICZ
UPI Senior Science Writer


SAN FRANCISCO, March 17 (UPI) -- Nutritionists are convinced that, just like
everyone else, children with attention-deficit/hyperactivity disorder are
what they eat.


Specifically, the specialists have their eye on so-called omega-3 fatty
acids as playing some role in the condition that, in general, is marked by
trouble keeping still, difficulty in maintaining attention, propensity
toward acting impulsively or some combination of the three.


Omega-3 fatty acids are plentiful in cold-water fish, such as salmon,
herring, tuna, clams, crab, cod, flounder, sole, halibut, catfish, trout and
shrimp. They also abound in nuts; soybeans; walnut, olive and flaxseed oil;
seeds; whole grains and dark leafy greens.


The fatty acids comprise a hefty component of the brain, which weighs in at
about 60-percent fat.


The compounds, which studies indicate are essential for forming and
maintaining the dopamine system, have been found in short supply in some,
though not all, children diagnosed with ADHD.


Many researchers see ADHD as a hereditary imbalance of brain chemicals, such
as dopamine -- which regulates movement, emotion, motivation and sensations
of pleasure.


That view is strongly contested by critics who point to a dearth of physical
evidence for such a notion.


Whatever their connection to the "feel-good" chemical in the brain, the
omega-3 fatty acids appear to have an impact on a child's behavior,
portending problems in youngsters who don't have enough of the compounds.


As one example, a recent Duke University study of 96 boys ages 6 to 12
indicated those with low blood levels of omega-3 fatty acids face increased
risk of ADHD-like behavior, learning and health challenges.


There is also some evidence the compounds may play a benevolent role in the
production of myelin, a protective insulation that coats the brain's
internal wiring,


A novel model of human brain development and degeneration proposed by
researchers at the University of California, Los Angeles implicates
disruption of myelin production in such childhood developmental disorders as
autism and ADHD.


From a review of scanned and autopsied brain tissue, the investigators
unraveled the role of myelin in these conditions.


Laden with more cholesterol than any other brain component, the sheet of fat
surrounds the spindly nerve-cell extensions called axons, permitting them to
carry messages to their neighbors in the safety and security of their armor.


The thicker and heavier the cells' coat, the faster and more effective their
communication, said team leader Dr. George Bartzokis, professor of neurology
at the David Geffen School of Medicine and director of the UCLA Memory
Disorders and Alzheimer's Disease Clinic and the Clinical Core of the UCLA
Alzheimer's Disease Research Center.


The pioneering neuroscientist discovered that myelin production continues
unabated throughout the first four decades of life before peaking and
plummeting at age 45. His latest research portrays the protective shield as
the neural system's Achilles' heel, vulnerable to a host of environmental
assaults.


"Myelination, a process uniquely elaborated in humans, arguably is the most
important and most vulnerable process of brain development as we mature and
age," Bartzokis said.


Without adequate insulation, cells won't connect properly, he has found in a
series of experiments that showed a breakdown in the sheath can expose the
naked wiring beneath and open the gates to an array of neurological and
behavioral problems.


Bartzokis's theory holds that humans "myelinate" different circuits at
various points in life, which could explain the sizeable differences between
brain diseases of the young and old.


An early disruption of the process, for instance, may throw for a loop the
development of the basic circuits that govern language and social
communication, two key impairments in autism.


A glitch during the early school years could hamper the ability to process
information efficiently and effectively, leading to deficits in attention
that characterize ADHD. Later in life, the result of a malfunction could be
Alzheimer's disease.


To Bartzokis, the human brain is akin to high-speed Internet.


"The speed, quality and bandwidth of the connections determine the brain's
ability to process information, and all these depend in large part on the
insulation that coats the brain's connecting wires," he said.


The findings may explain why developmental disorders leave no calling card
in the brain. "There's no dead anything on autopsy," Bartzokis said. "Those
brain connections just never developed normally."


Bartzokis's studies also show female brains make better myelin, which could
explain why boys are at much greater risk for autism, ADHD and other
problems.


"On the positive side, there are some interesting things to consider,"
Bartzokis said. "For example, essential fatty acids are fats that are
necessary for membrane production, and myelin is essentially pure membrane."


"They are called 'essential' because the human body cannot produce them,
and, therefore, they are like 'vitamins' -- they need to come from a good
diet," he added. "Thus, nutrition is very important because the brain is
very busy trying to build the myelin sheaths."


Still, researchers don't have the skinny on the exact relationship between
the fats and ADHD.


Although alternative medicine practitioners report some success in
ameliorating symptoms with the use of fatty acid, mineral, vitamin B and
other supplements, none of these has been embraced as standard therapy.


Conventional and complementary practices also part ways on the role, and
remedial potential, of food additives, sugar or allergens. All of these
remain controversial, having failed to withstand rigorous scientific
scrutiny, according to a compilation of ADHD data by Dr. Peter Jensen,
director of the Center for the Advancement of Children's Mental Health at
Columbia University.


Next: Seeking environmental clues to ADHD.


(Editors' Note: This series on ADHD is based on a review of hundreds of
reports and a survey of more than 200 specialists.)




In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.

You can visit the website of the AAP and learn for yourself.

There are
also psychological issues that are sometimes involved. These stem from
the socio-economic environment at school and home.

If there are psychological issues, then the proper diagnosis should
address them. They are NOT the basis for a proper AD/HD diagnosis.

Harsh medication is
not the answer to these problems.

True. Neither is a supplement. Addressing the psychological issues at home
and in school is important.

Don't believe the first word you
hear either.

Good advice for analyzing your post.

Research and make your decision when you have compiled a
vast amount of data. www.shaklee.net/waltongates

You would not be selling something, would you?

Jan Drew wrote:

"Mark Probert" wrote in message
...
Rick wrote:
The research into ADHD has shown that most children's diet has an
adverse effect on their ability to concentrate and learn.

Actually, the research into AD/HD shows that AD/HD has nothing to do with
diet.

Blatant repeated lie!


Still refusing to learn, Jan? Still accusing others of lying when they
disagree with you? How christian.

Do you have any reply to the relevant part of Mark's post:


"In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.


You can visit the website of the AAP and learn for yourself."


No?


Cathy



http://tinyurl.com/b2r6l

Foods and additives are common causes of the attention deficit hyperactive
disorder in children.


Boris M, Mandel FS.


North Shore Hospital-Cornell Medical Center, Manhasset, New York.


The attention deficit hyperactive disorder (ADHD) is a neurophysiologic
problem that is detrimental to children and their parents. Despite previous
studies on the role of foods, preservatives and artificial colorings in ADHD
this issue remains controversial. This investigation evaluated 26 children
who meet the criteria for ADHD. Treatment with a multiple item elimination
diet showed 19 children (73%) responded favorably, P .001. On open
challenge, all 19 children reacted to many foods, dyes, and/or
preservatives. A double-blind placebo controlled food challenge (DBPCFC) was
completed in 16 children. There was a significant improvement on placebo
days compared with challenge days (P = .003). Atopic children with ADHD had
a significantly higher response rate than the nonatopic group. This study
demonstrates a beneficial effect of eliminating reactive foods and
artificial colors in children with ADHD. Dietary factors may play a
significant role in the etiology of the majority of children with ADHD.


http://tinyurl.com/c2lez


The role of diet and behaviour in childhood.


Breakey J.


This short review summarizes the most important research, particularly that
from 1985 to 1995, on the relationship between diet and behaviour. Relevant
studies particularly those using double-blind placebo controlled food
challenge methodology were selected, and are presented within a historical
context. Summary tables of the early development of concepts and later
pertinent studies are provided. The research has shown that diet definitely
affects some children. Rather than becoming simpler the issue has become
demonstrably more complex. The range of suspect food items has broadened,
and some non-food items are relevant. Symptoms which may change include
those seen in attention deficit disorder (ADD) and attention deficit
hyperactivity disorder (ADHD), sleep problems and physical symptoms, with
later research emphasizing particularly changes in mood. The reports also
show the range of individual differences both in the food substances
producing reactions and in the areas of change.


http://tinyurl.com/cke6f


Controlled trial of cumulative behavioural effects of a common bread
preservative.


Dengate S, Ruben A.





OBJECTIVE: Many anecdotes and one scientific report describe cumulative
behavioural effects of bread preservative on children. METHODOLOGY:
Twenty-seven children, whose behaviour improved significantly on the Royal
Prince Alfred Hospital diet, which excludes food additives, natural
salicylates, amines and glutamates, were challenged with calcium propionate
(preservative code 282) or placebo through daily bread in a double-blind
placebo-controlled crossover trial. RESULTS: Due to four placebo responders,
there was no significant difference by ANOVA of weighted placebo and
challenge Rowe Behaviour Rating Inventory means, but a statistically
significant difference existed in the proportion of children whose
behaviours 'worsened' with challenge (52%), compared to the proportion whose
behaviour 'improved' with challenge (19%), relative to placebo (95%
confidence intervals 14-60%). CONCLUSIONS: Irritability, restlessness,
inattention and sleep disturbance in some children may be caused by a
preservative in healthy foods consumed daily. Minimizing the concentrations
added to processed foods would reduce adverse reactions. Testing for
behavioural toxicity should be included in food additive safety evaluation.


http://openpr.com/drucken/?id=1661

http://www.upi.com/ConsumerHealthDai...=20060316-0911...

Ped Med: The skinny on ADHD contributors
By LIDIA WASOWICZ
UPI Senior Science Writer


SAN FRANCISCO, March 17 (UPI) -- Nutritionists are convinced that, just like
everyone else, children with attention-deficit/hyperactivity disorder are
what they eat.


Specifically, the specialists have their eye on so-called omega-3 fatty
acids as playing some role in the condition that, in general, is marked by
trouble keeping still, difficulty in maintaining attention, propensity
toward acting impulsively or some combination of the three.


Omega-3 fatty acids are plentiful in cold-water fish, such as salmon,
herring, tuna, clams, crab, cod, flounder, sole, halibut, catfish, trout and
shrimp. They also abound in nuts; soybeans; walnut, olive and flaxseed oil;
seeds; whole grains and dark leafy greens.


The fatty acids comprise a hefty component of the brain, which weighs in at
about 60-percent fat.


The compounds, which studies indicate are essential for forming and
maintaining the dopamine system, have been found in short supply in some,
though not all, children diagnosed with ADHD.


Many researchers see ADHD as a hereditary imbalance of brain chemicals, such
as dopamine -- which regulates movement, emotion, motivation and sensations
of pleasure.


That view is strongly contested by critics who point to a dearth of physical
evidence for such a notion.


Whatever their connection to the "feel-good" chemical in the brain, the
omega-3 fatty acids appear to have an impact on a child's behavior,
portending problems in youngsters who don't have enough of the compounds.


As one example, a recent Duke University study of 96 boys ages 6 to 12
indicated those with low blood levels of omega-3 fatty acids face increased
risk of ADHD-like behavior, learning and health challenges.


There is also some evidence the compounds may play a benevolent role in the
production of myelin, a protective insulation that coats the brain's
internal wiring,


A novel model of human brain development and degeneration proposed by
researchers at the University of California, Los Angeles implicates
disruption of myelin production in such childhood developmental disorders as
autism and ADHD.


From a review of scanned and autopsied brain tissue, the investigators
unraveled the role of myelin in these conditions.


Laden with more cholesterol than any other brain component, the sheet of fat
surrounds the spindly nerve-cell extensions called axons, permitting them to
carry messages to their neighbors in the safety and security of their armor.


The thicker and heavier the cells' coat, the faster and more effective their
communication, said team leader Dr. George Bartzokis, professor of neurology
at the David Geffen School of Medicine and director of the UCLA Memory
Disorders and Alzheimer's Disease Clinic and the Clinical Core of the UCLA
Alzheimer's Disease Research Center.


The pioneering neuroscientist discovered that myelin production continues
unabated throughout the first four decades of life before peaking and
plummeting at age 45. His latest research portrays the protective shield as
the neural system's Achilles' heel, vulnerable to a host of environmental
assaults.


"Myelination, a process uniquely elaborated in humans, arguably is the most
important and most vulnerable process of brain development as we mature and
age," Bartzokis said.


Without adequate insulation, cells won't connect properly, he has found in a
series of experiments that showed a breakdown in the sheath can expose the
naked wiring beneath and open the gates to an array of neurological and
behavioral problems.


Bartzokis's theory holds that humans "myelinate" different circuits at
various points in life, which could explain the sizeable differences between
brain diseases of the young and old.


An early disruption of the process, for instance, may throw for a loop the
development of the basic circuits that govern language and social
communication, two key impairments in autism.


A glitch during the early school years could hamper the ability to process
information efficiently and effectively, leading to deficits in attention
that characterize ADHD. Later in life, the result of a malfunction could be
Alzheimer's disease.


To Bartzokis, the human brain is akin to high-speed Internet.


"The speed, quality and bandwidth of the connections determine the brain's
ability to process information, and all these depend in large part on the
insulation that coats the brain's connecting wires," he said.


The findings may explain why developmental disorders leave no calling card
in the brain. "There's no dead anything on autopsy," Bartzokis said. "Those
brain connections just never developed normally."


Bartzokis's studies also show female brains make better myelin, which could
explain why boys are at much greater risk for autism, ADHD and other
problems.


"On the positive side, there are some interesting things to consider,"
Bartzokis said. "For example, essential fatty acids are fats that are
necessary for membrane production, and myelin is essentially pure membrane."


"They are called 'essential' because the human body cannot produce them,
and, therefore, they are like 'vitamins' -- they need to come from a good
diet," he added. "Thus, nutrition is very important because the brain is
very busy trying to build the myelin sheaths."


Still, researchers don't have the skinny on the exact relationship between
the fats and ADHD.


Although alternative medicine practitioners report some success in
ameliorating symptoms with the use of fatty acid, mineral, vitamin B and
other supplements, none of these has been embraced as standard therapy.


Conventional and complementary practices also part ways on the role, and
remedial potential, of food additives, sugar or allergens. All of these
remain controversial, having failed to withstand rigorous scientific
scrutiny, according to a compilation of ADHD data by Dr. Peter Jensen,
director of the Center for the Advancement of Children's Mental Health at
Columbia University.


Next: Seeking environmental clues to ADHD.


(Editors' Note: This series on ADHD is based on a review of hundreds of
reports and a survey of more than 200 specialists.)




In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.

You can visit the website of the AAP and learn for yourself.

There are
also psychological issues that are sometimes involved. These stem from
the socio-economic environment at school and home.

If there are psychological issues, then the proper diagnosis should
address them. They are NOT the basis for a proper AD/HD diagnosis.

Harsh medication is
not the answer to these problems.

True. Neither is a supplement. Addressing the psychological issues at home
and in school is important.

Don't believe the first word you
hear either.

Good advice for analyzing your post.

Research and make your decision when you have compiled a
vast amount of data. www.shaklee.net/waltongates

You would not be selling something, would you?

cathyb wrote:
Jan Drew wrote:

"Mark Probert" wrote in message
...
Rick wrote:
The research into ADHD has shown that most children's diet has an
adverse effect on their ability to concentrate and learn.

Actually, the research into AD/HD shows that AD/HD has nothing to do with
diet.

Blatant repeated lie!


Still refusing to learn, Jan? Still accusing others of lying when they
disagree with you? How christian.

Do you have any reply to the relevant part of Mark's post:


"In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.


You can visit the website of the AAP and learn for yourself."


No?


Ya know, if she *really* wanted to be helpful in her research, she
could find information for me on how to help weak newborn goat kids.
I've got a beauty that arrived today, along with her twin sister.
She's half the size of her sister, she drank colostrum we milked from
her mother (another bad-bag nanny sigh) from the bottle, but now
she's acting really weak.

I've got my alarm set for 2 hrs from now so I can check her progress.

Of course, her twin sister is twice her size, hasn't eaten as much, and
seems to be doing much better.

Now if I can figure out just what it is that Shadow's doing. Silly
lamb seems to be nibbling on the boxes Chewy broke down to line the
sides of the playpen the new babies are in.

Kitten

Caitriona Mac Fhiodhbhuidhe wrote:
cathyb wrote:
Jan Drew wrote:

"Mark Probert" wrote in message
...
Rick wrote:
The research into ADHD has shown that most children's diet has an
adverse effect on their ability to concentrate and learn.

Actually, the research into AD/HD shows that AD/HD has nothing to do with
diet.

Blatant repeated lie!


Still refusing to learn, Jan? Still accusing others of lying when they
disagree with you? How christian.

Do you have any reply to the relevant part of Mark's post:


"In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.


You can visit the website of the AAP and learn for yourself."


No?


Ya know, if she *really* wanted to be helpful in her research, she
could find information for me on how to help weak newborn goat kids.
I've got a beauty that arrived today, along with her twin sister.
She's half the size of her sister, she drank colostrum we milked from
her mother (another bad-bag nanny sigh) from the bottle, but now
she's acting really weak.

I've got my alarm set for 2 hrs from now so I can check her progress.

Of course, her twin sister is twice her size, hasn't eaten as much, and
seems to be doing much better.

Now if I can figure out just what it is that Shadow's doing. Silly
lamb seems to be nibbling on the boxes Chewy broke down to line the
sides of the playpen the new babies are in.

Way off-topic, Kitten; but tell me, do you make goats' cheese? I can
only imagine that home-made goats' cheese would be even more superb
than the ridiculously expensive (but nice) French stuff we get here in
Oz.

Or do you save all of your goats' milk for the kids? (Not yours;
theirs!)

Cathy


Kitten

"cathyb" wrote in message
ups.com...

Jan Drew wrote:
"Mark Probert" wrote in message
...
Rick wrote:
The research into ADHD has shown that most children's diet has an
adverse effect on their ability to concentrate and learn.

Actually, the research into AD/HD shows that AD/HD has nothing to do
with
diet.

Blatant repeated lie!

Still refusing to learn, Jan?

Never.

No comment on Mark's blatant lie?

Still accusing other's of lying when they disagree with you?

No, that is a repeated lie.

How christian.

Thanks.

Indeed it is Christian to call lies.


Do you have any reply to the relevant part of Mark's post:

"In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.

You can visit the website of the AAP and learn for yourself."

No?

No. There is no need.

I posted the truth. There is more below.

Which most DEFINITELY proves Mark blatantly lied.

This is NOT a matter of disagreement.

Which shows your BLATANT REPEATED LIE.

AND

Your refusal to learn [not only from that], but.. from the sites I posted

No comment on those is noted.

AND

Your accusing me of EXACTLY what YOU are guilty of.

Jan

Cathy


http://tinyurl.com/b2r6l

Foods and additives are common causes of the attention deficit
hyperactive
disorder in children.


Boris M, Mandel FS.


North Shore Hospital-Cornell Medical Center, Manhasset, New York.


The attention deficit hyperactive disorder (ADHD) is a neurophysiologic
problem that is detrimental to children and their parents. Despite
previous
studies on the role of foods, preservatives and artificial colorings in
ADHD
this issue remains controversial. This investigation evaluated 26
children
who meet the criteria for ADHD. Treatment with a multiple item
elimination
diet showed 19 children (73%) responded favorably, P .001. On open
challenge, all 19 children reacted to many foods, dyes, and/or
preservatives. A double-blind placebo controlled food challenge (DBPCFC)
was
completed in 16 children. There was a significant improvement on placebo
days compared with challenge days (P = .003). Atopic children with ADHD
had
a significantly higher response rate than the nonatopic group. This study
demonstrates a beneficial effect of eliminating reactive foods and
artificial colors in children with ADHD. Dietary factors may play a
significant role in the etiology of the majority of children with ADHD.


http://tinyurl.com/c2lez


The role of diet and behaviour in childhood.


Breakey J.


This short review summarizes the most important research, particularly
that
from 1985 to 1995, on the relationship between diet and behaviour.
Relevant
studies particularly those using double-blind placebo controlled food
challenge methodology were selected, and are presented within a
historical
context. Summary tables of the early development of concepts and later
pertinent studies are provided. The research has shown that diet
definitely
affects some children. Rather than becoming simpler the issue has become
demonstrably more complex. The range of suspect food items has broadened,
and some non-food items are relevant. Symptoms which may change include
those seen in attention deficit disorder (ADD) and attention deficit
hyperactivity disorder (ADHD), sleep problems and physical symptoms, with
later research emphasizing particularly changes in mood. The reports also
show the range of individual differences both in the food substances
producing reactions and in the areas of change.


http://tinyurl.com/cke6f


Controlled trial of cumulative behavioural effects of a common bread
preservative.


Dengate S, Ruben A.





OBJECTIVE: Many anecdotes and one scientific report describe cumulative
behavioural effects of bread preservative on children. METHODOLOGY:
Twenty-seven children, whose behaviour improved significantly on the
Royal
Prince Alfred Hospital diet, which excludes food additives, natural
salicylates, amines and glutamates, were challenged with calcium
propionate
(preservative code 282) or placebo through daily bread in a double-blind
placebo-controlled crossover trial. RESULTS: Due to four placebo
responders,
there was no significant difference by ANOVA of weighted placebo and
challenge Rowe Behaviour Rating Inventory means, but a statistically
significant difference existed in the proportion of children whose
behaviours 'worsened' with challenge (52%), compared to the proportion
whose
behaviour 'improved' with challenge (19%), relative to placebo (95%
confidence intervals 14-60%). CONCLUSIONS: Irritability, restlessness,
inattention and sleep disturbance in some children may be caused by a
preservative in healthy foods consumed daily. Minimizing the
concentrations
added to processed foods would reduce adverse reactions. Testing for
behavioural toxicity should be included in food additive safety
evaluation.


http://openpr.com/drucken/?id=1661

http://www.upi.com/ConsumerHealthDai...=20060316-0911...

Ped Med: The skinny on ADHD contributors
By LIDIA WASOWICZ
UPI Senior Science Writer


SAN FRANCISCO, March 17 (UPI) -- Nutritionists are convinced that, just
like
everyone else, children with attention-deficit/hyperactivity disorder are
what they eat.


Specifically, the specialists have their eye on so-called omega-3 fatty
acids as playing some role in the condition that, in general, is marked
by
trouble keeping still, difficulty in maintaining attention, propensity
toward acting impulsively or some combination of the three.


Omega-3 fatty acids are plentiful in cold-water fish, such as salmon,
herring, tuna, clams, crab, cod, flounder, sole, halibut, catfish, trout
and
shrimp. They also abound in nuts; soybeans; walnut, olive and flaxseed
oil;
seeds; whole grains and dark leafy greens.


The fatty acids comprise a hefty component of the brain, which weighs in
at
about 60-percent fat.


The compounds, which studies indicate are essential for forming and
maintaining the dopamine system, have been found in short supply in some,
though not all, children diagnosed with ADHD.


Many researchers see ADHD as a hereditary imbalance of brain chemicals,
such
as dopamine -- which regulates movement, emotion, motivation and
sensations
of pleasure.


That view is strongly contested by critics who point to a dearth of
physical
evidence for such a notion.


Whatever their connection to the "feel-good" chemical in the brain, the
omega-3 fatty acids appear to have an impact on a child's behavior,
portending problems in youngsters who don't have enough of the compounds.


As one example, a recent Duke University study of 96 boys ages 6 to 12
indicated those with low blood levels of omega-3 fatty acids face
increased
risk of ADHD-like behavior, learning and health challenges.


There is also some evidence the compounds may play a benevolent role in
the
production of myelin, a protective insulation that coats the brain's
internal wiring,


A novel model of human brain development and degeneration proposed by
researchers at the University of California, Los Angeles implicates
disruption of myelin production in such childhood developmental disorders
as
autism and ADHD.


From a review of scanned and autopsied brain tissue, the investigators
unraveled the role of myelin in these conditions.


Laden with more cholesterol than any other brain component, the sheet of
fat
surrounds the spindly nerve-cell extensions called axons, permitting them
to
carry messages to their neighbors in the safety and security of their
armor.


The thicker and heavier the cells' coat, the faster and more effective
their
communication, said team leader Dr. George Bartzokis, professor of
neurology
at the David Geffen School of Medicine and director of the UCLA Memory
Disorders and Alzheimer's Disease Clinic and the Clinical Core of the
UCLA
Alzheimer's Disease Research Center.


The pioneering neuroscientist discovered that myelin production continues
unabated throughout the first four decades of life before peaking and
plummeting at age 45. His latest research portrays the protective shield
as
the neural system's Achilles' heel, vulnerable to a host of environmental
assaults.


"Myelination, a process uniquely elaborated in humans, arguably is the
most
important and most vulnerable process of brain development as we mature
and
age," Bartzokis said.


Without adequate insulation, cells won't connect properly, he has found
in a
series of experiments that showed a breakdown in the sheath can expose
the
naked wiring beneath and open the gates to an array of neurological and
behavioral problems.


Bartzokis's theory holds that humans "myelinate" different circuits at
various points in life, which could explain the sizeable differences
between
brain diseases of the young and old.


An early disruption of the process, for instance, may throw for a loop
the
development of the basic circuits that govern language and social
communication, two key impairments in autism.


A glitch during the early school years could hamper the ability to
process
information efficiently and effectively, leading to deficits in attention
that characterize ADHD. Later in life, the result of a malfunction could
be
Alzheimer's disease.


To Bartzokis, the human brain is akin to high-speed Internet.


"The speed, quality and bandwidth of the connections determine the
brain's
ability to process information, and all these depend in large part on the
insulation that coats the brain's connecting wires," he said.


The findings may explain why developmental disorders leave no calling
card
in the brain. "There's no dead anything on autopsy," Bartzokis said.
"Those
brain connections just never developed normally."


Bartzokis's studies also show female brains make better myelin, which
could
explain why boys are at much greater risk for autism, ADHD and other
problems.


"On the positive side, there are some interesting things to consider,"
Bartzokis said. "For example, essential fatty acids are fats that are
necessary for membrane production, and myelin is essentially pure
membrane."


"They are called 'essential' because the human body cannot produce them,
and, therefore, they are like 'vitamins' -- they need to come from a good
diet," he added. "Thus, nutrition is very important because the brain is
very busy trying to build the myelin sheaths."


Still, researchers don't have the skinny on the exact relationship
between
the fats and ADHD.


Although alternative medicine practitioners report some success in
ameliorating symptoms with the use of fatty acid, mineral, vitamin B and
other supplements, none of these has been embraced as standard therapy.


Conventional and complementary practices also part ways on the role, and
remedial potential, of food additives, sugar or allergens. All of these
remain controversial, having failed to withstand rigorous scientific
scrutiny, according to a compilation of ADHD data by Dr. Peter Jensen,
director of the Center for the Advancement of Children's Mental Health at
Columbia University.


Next: Seeking environmental clues to ADHD.


(Editors' Note: This series on ADHD is based on a review of hundreds of
reports and a survey of more than 200 specialists.)


http://seven.com.au/todaytonight/story/?id=22499

http://www.cspinet.org/new/adhdpr.html

http://www.13wham.com/health/local/s...C-DD64D08BE20A




In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.

You can visit the website of the AAP and learn for yourself.

There are
also psychological issues that are sometimes involved. These stem from
the socio-economic environment at school and home.

If there are psychological issues, then the proper diagnosis should
address them. They are NOT the basis for a proper AD/HD diagnosis.

Harsh medication is
not the answer to these problems.

True. Neither is a supplement. Addressing the psychological issues at
home
and in school is important.

Don't believe the first word you
hear either.

Good advice for analyzing your post.

Research and make your decision when you have compiled a
vast amount of data. www.shaklee.net/waltongates

You would not be selling something, would you?

Jan Drew wrote:
"cathyb" wrote in message
ups.com...

Jan Drew wrote:
"Mark Probert" wrote in message
...
Rick wrote:
The research into ADHD has shown that most children's diet has an
adverse effect on their ability to concentrate and learn.

Actually, the research into AD/HD shows that AD/HD has nothing to do
with
diet.

Blatant repeated lie!

Still refusing to learn, Jan?

Never.

No comment on Mark's blatant lie?

Still accusing other's of lying when they disagree with you?

No, that is a repeated lie.

How christian.

Thanks.

Indeed it is Christian to call lies.


Do you have any reply to the relevant part of Mark's post:

"In fact, the diagnostic protocol as set forth by the AAP
requires that ALL (that would include diet) causes of the behaviors be
ruled out before a diagnosis of AD/HD can be made.

You can visit the website of the AAP and learn for yourself."

No?

No. There is no need.

The fact that you have no argument is noted.

snip