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#1
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SIDS Genetic Link
http://news.yahoo.com/news?tmpl=stor...s_dc&printer=1
New Genetic Link Found to Crib Deaths By Maggie Fox, Health and Science Correspondent WASHINGTON (Reuters) - A collection of genes involved in early development may help explain why black babies are more at risk of sudden infant death syndrome than other U.S. groups, researchers said on Thursday. Yahoo! Health Have questions about your health? Find answers here. The gene mutations may also help explain why thousands of U.S. infants still succumb each year to SIDS, also known as crib death or cot death, despite education campaigns that have cut the rate in half, the researchers said. Dr. Debra Weese-Mayer, a professor of pediatrics at Rush University Medical Center in Chicago, said the finding does not fully explain the unexpected deaths of 3,000 U.S. infants a year, but helps explain some of the underlying biology. "For years everyone said SIDS was a mystery, but to me it is a puzzle and each of our studies fits in another piece," Weese-Mayer said in a telephone interview. "This is one more critical piece of information that tells us we are on the right path." Writing in the September issue of Pediatric Research, Weese-Mayer and colleagues at the University of Pittsburgh and elsewhere said they compared genetic material from 92 SIDS cases to that of 92 healthy one-year-olds. They looked specifically at genes involved in the development of the autonomic nervous system, which controls breathing, heartbeat and other involuntary functions. "If you have dysregulation of the autonomic nervous system, possibly in a stressful situation you don't have resiliency," she said. Heart rate and breathing may not be able to adapt quickly and may simply shut down -- which is what happens to SIDS babies. SAME MUTATION The researchers found 11 different mutations in 14 of the 92 SIDS cases but only one mutation -- the same one -- in two of the 92 healthy babies. "The curiosity is that 71 percent of the SIDS cases that had the mutation were African-American and both controls (healthy babies that had it) were African-American," she said. "Knowing that the SIDS incidence is significantly higher in African-Americans gives strong support for the possibility of a genetic basis." Other researchers have found different genes that may be involved in SIDS. In July a team at the Translational Genomics Research Institute in Phoenix, Arizona, found a new disorder in Amish families from Pennsylvania that causes sudden infant death and sometimes malformation of the genitals. In 2000 and 2001 researchers in the United States and Japan found a role for the serotonin transporter gene promoter in the brainstems of SIDS victims. While SIDS is a general term for unexplained infant deaths, doctors suspect a variety of causes. U.S. and British campaigns to teach parents and caretakers to have babies sleep on their backs cut SIDS deaths in half, but did not eradicate them. "We have had too many parents who came to us and said 'look, we did everything right -- we got the best prenatal care, no one smoked anywhere near the baby, we never put her down on her tummy and still she died,"' Weese-Mayer said. "That led us to say there has to be a genetic basis." The tissue from the SIDS babies was donated anonymously, so Weese-Mayer says she cannot tell if the gene mutations her team found run in families. She hopes the government might sponsor a large study to see how common the genetic mutations are in the population as a whole. That will help determine whether the mutations actually cause SIDS, she said. |
#2
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Wow, it's more than just a "link".....
http://www.kcbd.com/Global/story.asp?S=2066614 Quote: Researchers have uncovered what may be the first direct genetic link to why some babies suffer from sudden death. Scientists at the Genomics Research Institute say what they have found guarantees death in the first year of life. "If an individual inherits two broken copies of gene, they will die before their first birthday with 100% probability," says Dr. Dietrich A. Stephan, SIDS researcher. |
#3
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"CWatters" wrote in message ... Wow, it's more than just a "link"..... http://www.kcbd.com/Global/story.asp?S=2066614 Quote: Researchers have uncovered what may be the first direct genetic link to why some babies suffer from sudden death. Scientists at the Genomics Research Institute say what they have found guarantees death in the first year of life. "If an individual inherits two broken copies of gene, they will die before their first birthday with 100% probability," says Dr. Dietrich A. Stephan, SIDS researcher. I guess that the anti-vac liars wil now have to move on and find another scary thing to fearmonger over. |
#4
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"M,a,r,k P,r,o,b,e,r,t-August 20, 2004" M,a,r,k P,r,o,b,e,r,t wrote in message I guess that the anti-vac liars wil now have to move on and find another scary thing to fearmonger over. Oh I am disapointed in you. I don't think this research suggests that ALL (or even the majority of) cases of SID are caused by these genes. eg It doesn't preclude other causes like smoking. |
#5
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"CWatters" wrote in message ... "M,a,r,k P,r,o,b,e,r,t-August 20, 2004" M,a,r,k P,r,o,b,e,r,t wrote in message I guess that the anti-vac liars wil now have to move on and find another scary thing to fearmonger over. Oh I am disapointed in you. I don't think this research suggests that ALL (or even the majority of) cases of SID are caused by these genes. eg It doesn't preclude other causes like smoking. I know. However, I never miss an opportunity to take a shot at the anti-vac liars. At leat we can now ask them to prove it was not genetic... |
#7
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"Jeff" wrote in message ... "M,a,r,k P,r,o,b,e,r,t-August 20, 2004" M,a,r,k P,r,o,b,e,r,t wrote in message . net... "CWatters" wrote in message ... "M,a,r,k P,r,o,b,e,r,t-August 20, 2004" M,a,r,k P,r,o,b,e,r,t wrote in message I guess that the anti-vac liars wil now have to move on and find another scary thing to fearmonger over. Oh I am disapointed in you. I don't think this research suggests that ALL (or even the majority of) cases of SID are caused by these genes. eg It doesn't preclude other causes like smoking. I know. However, I never miss an opportunity to take a shot at the anti-vac liars. At leat we can now ask them to prove it was not genetic... I think a lot of anti-vac people are not liars -- they are just clueless, like that idiot from whale to. The results also don't eplain why kids who are put on their backs to sleep are less likely to die than those who sleep on their stomachs or why kids who parents smoke are less likely to see their first birthday. In other words, a genetic component does not mean there things that can be done to prevent SIDS. I meant, in other words, a genetic component does not mean there are not things that can't be done to prevent SIDS. Not smoking and putting kids to sleep on their backs both prevent kids from dying from SIDS. Knowing about a genetic component doesn't change this. Jeff Jeff |
#8
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"Jeff" wrote in message ... "M,a,r,k P,r,o,b,e,r,t-August 20, 2004" M,a,r,k P,r,o,b,e,r,t wrote in message . net... "CWatters" wrote in message ... "M,a,r,k P,r,o,b,e,r,t-August 20, 2004" M,a,r,k P,r,o,b,e,r,t wrote in message I guess that the anti-vac liars wil now have to move on and find another scary thing to fearmonger over. Oh I am disapointed in you. I don't think this research suggests that ALL (or even the majority of) cases of SID are caused by these genes. eg It doesn't preclude other causes like smoking. I know. However, I never miss an opportunity to take a shot at the anti-vac liars. At leat we can now ask them to prove it was not genetic... I think a lot of anti-vac people are not liars -- they are just clueless, like that idiot from whale to. He has been shown how wrong his site is so many times, that he is both an idiot and a liar. The results also don't explain why kids who are put on their backs to sleep are less likely to die than those who sleep on their stomachs or why kids who parents smoke are less likely to see their first birthday. In other words, a genetic component does not mean there things that can be done to prevent SIDS. Agreed. Genetics can explain some SIDS, not all, but vaccines are not the answer. |
#9
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"M,a,r,k P,r,o,b,e,r,t-August 21, 2004" M,a,r,k P,r,o,b,e,r,t wrote in message t... "Jeff" wrote in message ... "M,a,r,k P,r,o,b,e,r,t-August 20, 2004" M,a,r,k P,r,o,b,e,r,t wrote in message . net... "CWatters" wrote in message ... "M,a,r,k P,r,o,b,e,r,t-August 20, 2004" M,a,r,k P,r,o,b,e,r,t wrote in message I guess that the anti-vac liars wil now have to move on and find another scary thing to fearmonger over. Oh I am disapointed in you. I don't think this research suggests that ALL (or even the majority of) cases of SID are caused by these genes. eg It doesn't preclude other causes like smoking. I know. However, I never miss an opportunity to take a shot at the anti-vac liars. At leat we can now ask them to prove it was not genetic... I think a lot of anti-vac people are not liars -- they are just clueless, like that idiot from whale to. He has been shown how wrong his site is so many times, that he is both an idiot and a liar. Just because it was explained to John doesn't mean he understood. John could argue that he has explained to us that vaccine are dangerous so much that we are liars. But perserverence does not equal truth. The results also don't explain why kids who are put on their backs to sleep are less likely to die than those who sleep on their stomachs or why kids who parents smoke are less likely to see their first birthday. In other words, a genetic component does not mean there things that can be done to prevent SIDS. Agreed. Genetics can explain some SIDS, not all, but vaccines are not the answer. Sorry, I lost you. what do vaccines have to do with SIDS? I was talking about not smoking around babies and putting them on their backs to sleep. Not smoking and putting kids back to sleep have been shown to preserve human life. To my knowledge, vaccines have not been shown to affect the rate of SIDS (although they have saved millions of lives and all but stoped polio, measles, smallpox, rubella-related birth defects and other illnesses in the US). Jeff |
#10
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"CWatters" ) writes: Researchers have uncovered what may be the first direct genetic link to why some babies suffer from sudden death. Scientists at the Genomics Research Institute say what they have found guarantees death in the first year of life. "If an individual inherits two broken copies of gene, they will die before their first birthday with 100% probability," says Dr. Dietrich A. Stephan, SIDS researcher. I'm not convinced of that 100% probability. Nobody can predict the future. If the baby is able to live for a few months -- why shouldn't that baby be able to live longer? Maybe the baby is deficient in certain enzymes; well, maybe nutrients or other substances can be supplied to the baby to keep the baby alive, as we supply insulin to diabetics. It wouldn't surprise me if babies with those genes would live longer if they were given larger amounts of vitamin C. (Maybe there's something else they need too.) I believe that vitamin C deficiency is a major factor in SIDS. (See the book "Every Second Child" by A. Kalokerinos.) Dr. Kalokerinos found very high rates of SIDS in parts of Australia where vitamin C was very deficient in the diet. Vitamin C is needed by the body to produce neurotransmitters such as serotonin from raw materials in the diet such as tryptophan. If there's very little or no vitamin C in the brain, the brain can't make serotonin etc. Without these neurotransmitters the brain can't send messages, such as messages to the heart and lungs to keep on breathing and beating. Most people don't get enough vitamin C for optimal health. When a person has an illness such as a cold, they need much larger amounts of vitamin C, because the immune system uses up vitamin C when fighting the illness. For more about vitamin C, I recommend the book "How to Live Longer and Feel Better" by Linus Pauling. -- Cathy |
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