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#31
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The Fluoroquinolone Drugs are the most toxic and dangerousantibiotic in clinical practice today.
On Mar 11, 6:06*pm, "Skeptic" wrote:
"ciprocripple" wrote in message ... *Real Dr.s continue to learn from their patients You are not my patient. *You are an overboard, melodramatic, quite possibly lying internet poster. ------------------------------------------------------------------------------------------------------ Reply - And I'm very glad I'm not your patient. With your ignorance and stupidity you have undoubtedly injured and harmed more patients than you will ever be aware of, but you probably don't care. You know what you think to be true, and have stopped learning a long time ago obviously. I wouldn't waste my time lying about matters as serious as this one. For you to say that proves that you have no other defense of your actions and have to resort to childish accusations of my intent here. I'm only trying to warn other potential victims of Dr's like you who continue to keep their tiny little minds closed tightly and never try to learn from their patients or the experiences of others. I see your type all the time in the medical system. Big ego and small mind. The all to common God complex. Try doing a little more research on these dangerous abx and do it with an open mind....if that's even possible. There are many drugs that have serious side effects that can harm a person, but none are as toxic or have harmed as many as the Fluoroquinolones have. I'll bet you anything that you don't even know that FQ's given with an nsaid or steroid are a deadly combination do you? Didn't think so. You are a pathetic excuse for a dr. I wouldn't let you treat my dog, and I feel very sorry for all the patients you have yet to harm. |
#32
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The Fluoroquinolone Drugs are the most toxic and dangerous antibiotic in clinical practice today.
Take your issues up with the big boys - like the text books that recommend
the FQ's as first line agent. Moron. |
#33
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The Fluoroquinolone Drugs are the most toxic and dangerousantibiotic in clinical practice today.
On Mar 16, 6:55*pm, "Skeptic" wrote:
Take your issues up with the big boys - like the text books that recommend the FQ's as *first line agent. *Moron. Reply - The same big boys that thought Viox was so great and harmless. The list goes on and on for drugs that were found out too late that they were killing people and destroying lives, even though it was stated otherwise in the textbooks. But, I guess if it's written in the text books that it sould be used as first line, well then it must be true. Geez, I wonder if the manufacturers had anything to do with that to maybe increase their sales..........you think?!? Naw, you don't think, you just believe everything you read in those text books. |
#34
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The Fluoroquinolone Drugs are the most toxic and dangerousantibiotic in clinical practice today.
Take your issues up with the big boys - like the text books that
recommend the FQ's as first line agent. Moron. Moron 1. a person who is notably stupid or lacking in good judgment. It would seem to me, by definition, that if a person is being warn about serious side effects, is provided with detail documentation, who then chooses to ignore such warnings would be the one considered to be a moron, not the one providing such warnings. Additionally the textbook state that the fluoroquinolones can and do cause renal calculus, but this person also chooses to ignore that text and states that they do not. Guess you just pick and choose what you care to use out of a textbook ignoring all the rest. To me this is indeed notably STUPID and LACKING IN GOOD JUDGMENT. So who here is calling the kettle black? Insults, putdowns, and harsh words, yet not one bit of proof being offered to support the counter arguments. That is indeed moronic. Text books at one time stated that the world was flat too. Doesn't mean it was. Relying upon textbooks while insulting the patients is way beyond stupid. It is retarded at best. Take your issues up with the big boys? Why? The textbooks you are using are horribly outdated and probalby out of print by now. Additionally they don't prescribe these drugs, and call their patients morons when they have side effects. Retarded morons like this do. Typical eight to twelve year old mentality. Calling the other person names. That is the second definition of moron: Moron (psychology), a person with a mental age between 8 and 12 Your killing us here...literally, moron. "Treatment with moxifloxacin is associated with a risk of developing fulminant hepatitis potentially leading to life threatening liver failure and risk of potentially life threatening bullous skin reactions like Stevens-Johnson-Syndrome (SJS) or toxic epidermal necrolysis (TEN)." While we are on the subject let's take a look at the latest Dear Doctor letter as well: This is a copy of the European Dear Doctor Letter February 2008 IMPORTANT INFORMATION REGARDING SERIOUS ADVERSE REACTIONS AND SAFETY MEASURES Direct Healthcare Professional Communication regarding moxifloxacin (Avelox(R)) and serious hepatic and bullous skin reactions Dear Healthcare Professional, In agreement with EU regulatory authorities, including the Medicines and Healthcare products Regulatory Agency (MHRA), Bayer would like to inform you of important safety information. A recent assessment of adverse reactions associated with the use of moxifloxacin resulted in the following information and recommendations: * Treatment with moxifloxacin is associated with a risk of developing fulminant hepatitis potentially leading to life threatening liver failure and risk of potentially life threatening bullous skin reactions like Stevens-Johnson-Syndrome (SJS) or toxic epidermal necrolysis (TEN). * Due to limited clinical data, moxifloxacin is contraindicated in patients with impaired liver function (Child Pugh C) and in patients with transaminases increased 5 fold the upper limit of normal (ULN). * Patients should be advised to stop treatment and to contact their physician if early signs and symptoms of these reactions occur. * The product information has been appropriately updated. * Healthcare professionals are encouraged to report any suspected adverse reactions associated with the use of moxifloxacin. Background Moxifloxacin is known to impair liver function, and the product information was updated to include Stevens-Johnson-Syndrome (SJS) in 2002. A review of worldwide serious, including fatal, cases of both hepatotoxicity and bullous skin reactions such as SJS and toxic epidermal necrolysis (TEN) reported for moxifloxacin was recently performed. Safety Concern The liver injuries possibly related to moxifloxacin were more frequently of cholestatic or mixed hepatocellular-cholestatic than of hepatocellular type. Onset of symptoms was usually between 3 and 10 days. Isolated cases of delayed hepatotoxic effects were also identified and usually occurred 5 to 30 days after cessation of moxifloxacin therapy. Eight reports of fatal hepatic injuries were considered as possibly related to moxifloxacin therapy. Cases of positive re-challenge gave further evidence of a causal relationship. However, the majority of patients experiencing serious liver injuries where the outcome was reported improved or recovered. TEN was reported in several cases where a causal relationship was considered possible; this included two cases with fatal outcome. Additionally, a total of 35 individual cases of SJS were reported, including three cases where there was a fatal outcome and seven cases which were considered life-threatening. In these 10 cases of severe SJS, a progression to TEN was documented in three patients. Based on the large patient exposure, the incidence of both life threatening liver injuries and TEN is very low, although a definite frequency cannot be calculated from these reports. As a consequence of this review, Bayer has revised the product information for moxifloxacin across the EU. Recommendations to Healthcare Professionals We would like to remind you that moxifloxacin is contraindicated in patients with impaired liver function (Child Pugh C) and in patients with transaminases increased 5 fold ULN. We would like to further remind you to be vigilant for the early signs and symptoms of severe liver injury and bullous skin reactions like SJS or TEN. Patients should be advised to stop treatment immediately and to contact a physician if relevant signs or symptoms occur, including rapidly developing asthenia associated with jaundice, dark urine, bleeding tendency and hepatic encephalopathy. When prescribing moxifloxacin, consideration should be given to official guidance on the appropriate use of antibacterial agents which is especially relevant with regard to treatment of less severe infections. Call for reporting If you have observed similar cases, please report adverse reactions to the MHRA or to Bayer HealthCare. Suspected adverse reactions should be reported directly to the MHRA via the Yellow Card Scheme (information can be found at Hwww.yellowcard.gov.ukH) or to Bayer HealthCare Drug Surveillance Department either by phone on 01635 563500, fax 01635 563703, by e- mail to . Communication information If you have any further questions please do not hesitate to contact Bayer HealthCare Medical Information department on 01635 563116 or by e-mail at . Yours sincerely, Medical Director Bayer Schering Pharma, Bayer plc "Treatment with moxifloxacin is associated with a risk of developing fulminant hepatitis potentially leading to life threatening liver failure and risk of potentially life threatening bullous skin reactions like Stevens-Johnson-Syndrome (SJS) or toxic epidermal necrolysis (TEN)." Guess you didn't read this either since it is not in one of your textbooks. Liver failure, SJS and TEN. If this is a safe drug what are we comparing this too? Arsenic? Oh I know, since this isn't Ciprofloxacin, this does not apply to the discussion at hand. Doesn't matter that this is a proven class effect. Not. Not at all since it isn't in the textbook must not be true. .. |
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