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#51
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Aspartame: RICO Complaint Filed Against NutraSweet, ADA, Monsanto
Max C. wrote:
Mark Probert wrote: Max C. wrote: Mark Probert wrote: Max C. wrote: Mark Probert wrote: Max C. wrote: Mark wrote: Max C. wrote: Peter Bowditch wrote: "Jan Drew" wrote: http://www.thenhf.com/articles_46.htm Aspartame: RICO Complaint Filed Against NutraSweet, ADA, Monsanto Sepp (Josef) Hasslberger September 17, 2004 That's over two years ago, Jan, and aspartame is still on the market. Whatever happened to the great court case? Could it be just possible that it went nowhere? I don't think something being on the market is any indication that it's safe. We FINALLY got the FDA to admit that trans fats are not safe in any amount, but they're still everywhere. There is no question to the validity of the claim aspartame, a dipeptide, breaks down into several chemicals, one being methanol, once inside the body. That methanol then breaks down into formaldehyde. I remember seeing this in an email and thinking to myself "No way. This has to be net lore." Then I happened to see the myth challenged on TV (I believe on the show Dr. Know) and sure enough, formaldehyde is a by product of aspartame. All one needs to do is search the web for aspartame and formaldehyde to see a list of side effects cause by constant use of aspartame. I'm surprised this is even a debating point these days. Max. No doubt your organic chemistry is top-notch, but I undoubtedly absorbed far more formaldehyde by dissecting frogs in high school and cadavers in medical school than I would ever ingest in a lifetime's consumption of Diet Pepsi. "Dose makes the poison" -- memorize that. Mark, MD Dose = poison also depends on on the toxicity of the item in question. Some compounds require extremely small doses to be poison, some require large amounts. Additionally, something does not have to kill you to be a poison. There are literally thousands of cases tying aspartame to migraine headaches. In this letter to the FDA : http://www.fda.gov/ohrms/dockets/dai...emc-000200.txt Mark Gold, chuckle...he posted to usenet years ago that there would be epidemics of people made blind by aspartame... the problems of the formation of aspartic acid, formaldehyde and methanol are discussed. Here you can see that serum levels of methanol go up after aspartame intake: http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract "The temporary serum methanol increase showed peak values within the range of individual basal levels." What does that mean? And this one: http://www.newstarget.com/004416.html has good general warnings about sodas in general, including some comments on aspartame. Newstarget? Not a credible source. Pure opinion. That's right... when you can't debate the issue, just attack the messenger. Works every time, huh. :-/ Debating NewsTarget articles is like debating the direction of sunrise. Then please feel free to debate any of the other actual studies I've posted or even to comment on the rebuttal of your study showing no link between aspartame and ADD. Aspartame linked to cancer. http://www.ehponline.org/docs/2005/8711/abstract.html "Abstract The Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation EVERYTHING they test seems to be carcinogenic. Weird. Makes me wonder... BTW, this outfit did not want to divulge the raw data for months... I certainly hope that's not your idea of evidence that aspartame is safe. Nope. It is my idea that the source of the evidence is, at best, questionable. BTW, Mark Lowry mentioned the rats. Those rats are bred to develop cancer and are HYPERSENSITIVE to anything and everything. The study, at the very best, merely suggests that some further testing should be done. These rats are far from human comparable. Max. has conducted a long-term bioassay on aspartame (APM) , a widely used artificial sweetener. APM was administered with feed to 8-week-old Sprague-Dawley rats (100-150/sex/group) , at concentrations of 100,000, 50,000, 10,000, 2,000, 400, 80, or 0 ppm. The treatment lasted until natural death, at which time all deceased animals underwent complete necropsy. Histopathologic evaluation of all pathologic lesions and of all organs and tissues collected was routinely performed on each animal of all experimental groups. The results of the study show for the first time that APM, in our experimental conditions, causes a) an increased incidence of malignant-tumor-bearing animals with a positive significant trend in males (p = 0.05) and in females (p = 0.01) , in particular those females treated at 50,000 ppm (p = 0.01) ; b) an increase in lymphomas and leukemias with a positive significant trend in both males (p = 0.05) and females (p = 0.01) , in particular in females treated at doses of 100,000 (p = 0.01) , 50,000 (p = 0.01) , 10,000 (p = 0.05) , 2,000 (p = 0.05) , or 400 ppm (p = 0.01) ; c) a statistically significant increased incidence, with a positive significant trend (p = 0.01) , of transitional cell carcinomas of the renal pelvis and ureter and their precursors (dysplasias) in females treated at 100,000 (p = 0.01) , 50,000 (p = 0.01) , 10,000 (p = 0.01) , 2,000 (p = 0.05) , or 400 ppm (p = 0.05) ; and d) an increased incidence of malignant schwannomas of peripheral nerves with a positive trend (p = 0.05) in males. The results of this mega-experiment indicate that APM is a multipotential carcinogenic agent, even at a daily dose of 20 mg/kg body weight, much less than the current acceptable daily intake. On the basis of these results, a reevaluation of the present guidelines on the use and consumption of APM is urgent and cannot be delayed. Key words: artificial sweetener, aspartame, carcinogenicity, lymphomas, malignant schwannomas, rats, renal pelvis carcinomas. Environ Health Perspect 114:379-385 (2006) . doi:10.1289/ehp.8711 available via http://dx.doi.org/ [Online 17 November 2005]" Max. |
#52
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Aspartame: RICO Complaint Filed Against NutraSweet, ADA, Monsanto
Mark Probert wrote: Max C. wrote: Mark Probert wrote: Max C. wrote: Mark Probert wrote: Max C. wrote: Mark Probert wrote: Max C. wrote: Mark wrote: Max C. wrote: Peter Bowditch wrote: "Jan Drew" wrote: http://www.thenhf.com/articles_46.htm Aspartame: RICO Complaint Filed Against NutraSweet, ADA, Monsanto Sepp (Josef) Hasslberger September 17, 2004 That's over two years ago, Jan, and aspartame is still on the market. Whatever happened to the great court case? Could it be just possible that it went nowhere? I don't think something being on the market is any indication that it's safe. We FINALLY got the FDA to admit that trans fats are not safe in any amount, but they're still everywhere. There is no question to the validity of the claim aspartame, a dipeptide, breaks down into several chemicals, one being methanol, once inside the body. That methanol then breaks down into formaldehyde. I remember seeing this in an email and thinking to myself "No way. This has to be net lore." Then I happened to see the myth challenged on TV (I believe on the show Dr. Know) and sure enough, formaldehyde is a by product of aspartame. All one needs to do is search the web for aspartame and formaldehyde to see a list of side effects cause by constant use of aspartame. I'm surprised this is even a debating point these days. Max. No doubt your organic chemistry is top-notch, but I undoubtedly absorbed far more formaldehyde by dissecting frogs in high school and cadavers in medical school than I would ever ingest in a lifetime's consumption of Diet Pepsi. "Dose makes the poison" -- memorize that. Mark, MD Dose = poison also depends on on the toxicity of the item in question. Some compounds require extremely small doses to be poison, some require large amounts. Additionally, something does not have to kill you to be a poison. There are literally thousands of cases tying aspartame to migraine headaches. In this letter to the FDA : http://www.fda.gov/ohrms/dockets/dai...emc-000200.txt Mark Gold, chuckle...he posted to usenet years ago that there would be epidemics of people made blind by aspartame... the problems of the formation of aspartic acid, formaldehyde and methanol are discussed. Here you can see that serum levels of methanol go up after aspartame intake: http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract "The temporary serum methanol increase showed peak values within the range of individual basal levels." What does that mean? And this one: http://www.newstarget.com/004416.html has good general warnings about sodas in general, including some comments on aspartame. Newstarget? Not a credible source. Pure opinion. That's right... when you can't debate the issue, just attack the messenger. Works every time, huh. :-/ Debating NewsTarget articles is like debating the direction of sunrise. Then please feel free to debate any of the other actual studies I've posted or even to comment on the rebuttal of your study showing no link between aspartame and ADD. Aspartame linked to cancer. http://www.ehponline.org/docs/2005/8711/abstract.html "Abstract The Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation EVERYTHING they test seems to be carcinogenic. Weird. Makes me wonder... BTW, this outfit did not want to divulge the raw data for months... I certainly hope that's not your idea of evidence that aspartame is safe. Nope. It is my idea that the source of the evidence is, at best, questionable. BTW, Mark Lowry mentioned the rats. Those rats are bred to develop cancer and are HYPERSENSITIVE to anything and everything. The study, at the very best, merely suggests that some further testing should be done. These rats are far from human comparable. First, by agreeing to Mark's claim, are you saying that there are no humans which might be more susceptible to cancer than others? Second, I've tried to verify the claim that a Sprague-Dawley rat would be "HYPERSENSITIVE to anything and everything." You know, I haven't found anything saying that. Here's what I've found so far: http://aceanimals.com/SpragueDawley.htm "The outbred multipurpose model of choice is the Sprague Dawley Rat. A general model for the study of human health and disease, this outbred rat serves as an excellent model for toxicology, reproduction, pharmacology, and behavioral research areas. Common characteristics of the Sprague Dawley Rat include: Anatomy and Physiology Adult body weight: 250 - 300g (female); 450 - 520g (male) Life span: 2.5 - 3.5 years Respiratory rate: 70 - 115 breaths/minute Heart rate: 250 - 450 beats/minute * The dental formulae is 2(I 1/1, M 3/3) = 16. The incisors are open-rooted and grow continuously. Rats will bite or "pinch" with their sharp incisors if mishandled. * The esophagus enters the stomach at the lesser curvature through a fold of tissue of the stomach. Because of this anatomical arrangement, the rat is unable to vomit. * Like the horse, the rat does not have a gall bladder. * The left lung consists of one lobe; the right lung consists of four lobes. * The rat has five pairs of mammary glands. Distribution of mammary tissue is diffuse, extending from the ventral midline over the flanks, thorax, and portions of the neck. * The urethra of the female rat does not communicate with the vagina or vulva; it exits separately just ventral to the vulva. * The deep gland of the nictitating membrane (Harderian gland) is a pigmented lacrimal gland located behind the eyeball, encircling the optic nerve. The secretion of this gland is rich in lipid and porphyrin. Although many species possess a Harderian gland, it assumes a special importance in the rat. During periods of stress and/or certain diseases, the tears overflow and stain the face around the eyes and nose. When the tears dry, the pigment has the appearance of dried blood. The pigment fluoresces under ultraviolet light and contains little or no blood. * The rat responds to decreases in ambient temperature by nonshivering thermogenesis, and to increases in ambient temperature by increasing the vascularization of its long tail, which may serve as a thermoregulatory organ. Nonshivering thermogenesis for the most part occurs in brown fat, the highest concentration of which is found in the subcutaneous tissues between the scapulae." http://www.ndif.org/Terms/Sprague-Dawley_rats.html "A strain of albino rats developed by the Sprague-Dawley Animal Company, widely used in experimental work because of their calmness and ease of handling." The rest of the links discuss actual studies with the rats. And you know, I found quite a few that made no mention of the rats getting cancer, even with very poor diets designed to initiate obesity. You'd think if they were hypersensitive to cancer, a diet specifically designed to induce obesity would set off some cancer. I would imagine (thought I don't know for sure) that it's possible to breed the rats to be more susceptible to cancer for specific studies, but if that was done in this case, what evidence do you have of that? Max. |
#53
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Aspartame: RICO Complaint Filed Against NutraSweet, ADA, Monsanto
I'm still waiting for clarification on the Sprague-Dawley rats, Mark
(either one of you.) You claimed that they would be "HYPERSENSITIVE to anything and everything" and that they are "are far from human comparable." I found just the opposite when when I found what appeared to be a breeder's site that said: "The outbred multipurpose model of choice is the Sprague Dawley Rat. A general model for the study of human health and disease, this outbred rat serves as an excellent model for toxicology, reproduction, pharmacology, and behavioral research areas. I had already posted that info, as you can see below. I'd like to know what information you have that shows that the rats used in the study in question were hypersensitive to cancer. Max. Max C. wrote: Mark Probert wrote: BTW, Mark Lowry mentioned the rats. Those rats are bred to develop cancer and are HYPERSENSITIVE to anything and everything. The study, at the very best, merely suggests that some further testing should be done. These rats are far from human comparable. First, by agreeing to Mark's claim, are you saying that there are no humans which might be more susceptible to cancer than others? Second, I've tried to verify the claim that a Sprague-Dawley rat would be "HYPERSENSITIVE to anything and everything." You know, I haven't found anything saying that. Here's what I've found so far: http://aceanimals.com/SpragueDawley.htm "The outbred multipurpose model of choice is the Sprague Dawley Rat. A general model for the study of human health and disease, this outbred rat serves as an excellent model for toxicology, reproduction, pharmacology, and behavioral research areas. Common characteristics of the Sprague Dawley Rat include: Anatomy and Physiology Adult body weight: 250 - 300g (female); 450 - 520g (male) Life span: 2.5 - 3.5 years Respiratory rate: 70 - 115 breaths/minute Heart rate: 250 - 450 beats/minute * The dental formulae is 2(I 1/1, M 3/3) = 16. The incisors are open-rooted and grow continuously. Rats will bite or "pinch" with their sharp incisors if mishandled. * The esophagus enters the stomach at the lesser curvature through a fold of tissue of the stomach. Because of this anatomical arrangement, the rat is unable to vomit. * Like the horse, the rat does not have a gall bladder. * The left lung consists of one lobe; the right lung consists of four lobes. * The rat has five pairs of mammary glands. Distribution of mammary tissue is diffuse, extending from the ventral midline over the flanks, thorax, and portions of the neck. * The urethra of the female rat does not communicate with the vagina or vulva; it exits separately just ventral to the vulva. * The deep gland of the nictitating membrane (Harderian gland) is a pigmented lacrimal gland located behind the eyeball, encircling the optic nerve. The secretion of this gland is rich in lipid and porphyrin. Although many species possess a Harderian gland, it assumes a special importance in the rat. During periods of stress and/or certain diseases, the tears overflow and stain the face around the eyes and nose. When the tears dry, the pigment has the appearance of dried blood. The pigment fluoresces under ultraviolet light and contains little or no blood. * The rat responds to decreases in ambient temperature by nonshivering thermogenesis, and to increases in ambient temperature by increasing the vascularization of its long tail, which may serve as a thermoregulatory organ. Nonshivering thermogenesis for the most part occurs in brown fat, the highest concentration of which is found in the subcutaneous tissues between the scapulae." http://www.ndif.org/Terms/Sprague-Dawley_rats.html "A strain of albino rats developed by the Sprague-Dawley Animal Company, widely used in experimental work because of their calmness and ease of handling." The rest of the links discuss actual studies with the rats. And you know, I found quite a few that made no mention of the rats getting cancer, even with very poor diets designed to initiate obesity. You'd think if they were hypersensitive to cancer, a diet specifically designed to induce obesity would set off some cancer. I would imagine (thought I don't know for sure) that it's possible to breed the rats to be more susceptible to cancer for specific studies, but if that was done in this case, what evidence do you have of that? Max. |
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