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Bread and Plants



 
 
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Old March 19th 08, 09:54 AM posted to sci.med.nutrition,misc.kids.health,alt.support.arthritis,misc.health.alternative,alt.support.chronic-pain
ironjustice
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Posts: 6
Default Bread and Plants

IP6 is phytate / phytic acid found in the chaff of your grains and
other plants.
Anthocyanins are all those colors you see in your plants.

"IP6 enhances gastrointestinal absorption of anthocyanins"

Enhanced absorption of anthocyanins after oral administration of
phytic acid in rats and humans. Mar 21, 2007
Hitoshi Matsumoto,Kyoko Ito,Kumiko Yonekura,Takanori Tsuda,Takashi
Ichiyanagi,Masao Hirayama,Tetsuya Konishi
Many studies on the bioavailability of polyphenols have been
reported.
However, the relative urinary excretions of AC are also low, ranging
from 0.004% to 0.1%. By contrast, other polyphenols show higher
urinary excretion levels.
Here, we studied the enhancing effects of phytic acid (IP6) on
absorption of blackcurrant anthocyanins (BCAs) in rats and humans.
In rats after oral administration of BCAs (as 241 mg of AC/kg body
weight) in IP6 (0%, 0.25%, 0.5%, 1%, 2.5%) solution, the ACs recovery
in urine was increased dependent on IP6 dose. These results suggest
that the IP6 enhances gastrointestinal absorption of ACs.
At the further analysis of IP6 enhancement effect in rat, whereas BCAs
were normally passed through the stomach and duodenum within 2 h, in
IP6 group, after 2-6 h post-administration, stomach and jejunum
content's weights were specifically heavy, and large amounts of ACs
were also detected in stomach, duodenum, and jejunum.
These results suggested that the mixture of BCAs and IP6 reduced the
gastrointestinal motility. Prolongation of ACs residue in
gastrointestinal tract then caused the enhancing effects of IP6 on
absorption of AC.
In the human study, each subject was orally administrated a BCA
beverage containing BCA concentrate (AC 4 mg/kg body weight), 1% of
IP6, and 1% of sodium citrate as a pH stabilizer. Both the plasma
level and the urinary excretion of AC were increased as compared to
BCA administration without IP6.
AC intake with IP6 may increase the bioavailability of AC to the
comparative level as other polyphenols.
Yet, phytic acid, being a strong chelator of important minerals,
contributes to mineral deficiencies.
An interference with iron uptake has been reported. Safety tests are
therefore necessary before high dose IP6 can be used in foods.


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