If this is your first visit, be sure to check out the FAQ by clicking the link above. You may have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. |
|
|
Thread Tools | Display Modes |
#1
|
|||
|
|||
Ritalin and Liver cancer
http://www.preventcancer.com/patient...id/ritalin.htm American Academy of Pediatrics Guidelines for Treating Behavioral Disorders in Children with Ritalin Ignores Evidence of Cancer Risks warns Samuel S. Epstein, M.D. Chicago, 10/04/01. Based on an industry-funded multi-university trial on 282 pre-teen children treated with Ritalin for attention deficit/hyperactivity disorders (ADHD), just published in Pediatrics, the American Academy of Pediatrics has endorsed the use of the drug. However, the Academy ignores clear evidence of the drug's cancer risks of which parents, teachers and school nurses, besides most pediatricians and psychiatrists, still remain uninformed and unaware. Some 40 years after the drug was first marketed by Ciba Geigy, carcinogenicity tests were conducted at the taxpayers expense by the National Toxicology Program, the results of which were published in 1995. Adult mice were fed Ritalin over a two-year period at dosages close to those prescribed to children. The mice developed a statistically significant incidence of liver abnormalities and tumors, including highly aggressive rare cancers known as hepatoblastomas. These findings are particularly disturbing as the tests were conducted on adult, rather than young mice which would be expected to be much more sensitive to carcinogenic effects. The National Toxicology Program concluded that Ritalin is a "possible human carcinogen," and recommended the need for further research. While still insisting that the drug is safe, the Food and Drug Administration admitted that these findings signal "carcinogenic potential," and required a statement to this effect in the drug's package insert. However, these inserts are not seen by parents or nurses. The Physicians' Desk Reference admits evidence on the carcinogenicity of Ritalin, now manufactured by Novartis, qualified by the statement that "the significance of these results is unknown," apparently not recognizing that this is more alarming than reassuring. Apart from cancer risks, there is also suggestive evidence that Ritalin induces genetic damage in blood cells of Ritalin-treated children. Concerns on Ritalin's cancer risk are more acute in view of the millions of children treated annually with the drug and the escalating incidence of childhood cancer, by some 35% over the last few decades, quite apart from delayed risks of cancer in adult life. These risks are compounded by the availability of alternative safe and effective procedures, notably behavior modification and biofeedback. There is no justification for prescribing Ritalin, even by highly qualified pediatricians and psychiatrists, unless parents have been explicitly informed of the drug's cancer risks. Otherwise, prescribing Ritalin constitutes unarguable medical malpractice. CONTACT: Samuel S. Epstein, M.D. Professor emeritus Environmental & Occupational Medicine Chairman, Cancer Prevention Coalition c/o University of Illinois at Chicago School of Public Health, M/C 922 2121 W. Taylor Street Chicago, IL 60612 phone 312-996-2297, fax 312-413-9898 |
#2
|
|||
|
|||
this was 3 1/2 years ago. Try more modern news next time.
Jeff |
#3
|
|||
|
|||
wow, very frightening and very relevant for anyone taking ritalin. On 6 May 2005 19:22:57 -0700, in misc.kids.breastfeeding "Tim Campbell" wrote: http://www.preventcancer.com/patient...id/ritalin.htm American Academy of Pediatrics Guidelines for Treating Behavioral Disorders in Children with Ritalin Ignores Evidence of Cancer Risks warns Samuel S. Epstein, M.D. Chicago, 10/04/01. Based on an industry-funded multi-university trial on 282 pre-teen children treated with Ritalin for attention deficit/hyperactivity disorders (ADHD), just published in Pediatrics, the American Academy of Pediatrics has endorsed the use of the drug. However, the Academy ignores clear evidence of the drug's cancer risks of which parents, teachers and school nurses, besides most pediatricians and psychiatrists, still remain uninformed and unaware. Some 40 years after the drug was first marketed by Ciba Geigy, carcinogenicity tests were conducted at the taxpayers expense by the National Toxicology Program, the results of which were published in 1995. Adult mice were fed Ritalin over a two-year period at dosages close to those prescribed to children. The mice developed a statistically significant incidence of liver abnormalities and tumors, including highly aggressive rare cancers known as hepatoblastomas. These findings are particularly disturbing as the tests were conducted on adult, rather than young mice which would be expected to be much more sensitive to carcinogenic effects. The National Toxicology Program concluded that Ritalin is a "possible human carcinogen," and recommended the need for further research. While still insisting that the drug is safe, the Food and Drug Administration admitted that these findings signal "carcinogenic potential," and required a statement to this effect in the drug's package insert. However, these inserts are not seen by parents or nurses. The Physicians' Desk Reference admits evidence on the carcinogenicity of Ritalin, now manufactured by Novartis, qualified by the statement that "the significance of these results is unknown," apparently not recognizing that this is more alarming than reassuring. Apart from cancer risks, there is also suggestive evidence that Ritalin induces genetic damage in blood cells of Ritalin-treated children. Concerns on Ritalin's cancer risk are more acute in view of the millions of children treated annually with the drug and the escalating incidence of childhood cancer, by some 35% over the last few decades, quite apart from delayed risks of cancer in adult life. These risks are compounded by the availability of alternative safe and effective procedures, notably behavior modification and biofeedback. There is no justification for prescribing Ritalin, even by highly qualified pediatricians and psychiatrists, unless parents have been explicitly informed of the drug's cancer risks. Otherwise, prescribing Ritalin constitutes unarguable medical malpractice. CONTACT: Samuel S. Epstein, M.D. Professor emeritus Environmental & Occupational Medicine Chairman, Cancer Prevention Coalition c/o University of Illinois at Chicago School of Public Health, M/C 922 2121 W. Taylor Street Chicago, IL 60612 phone 312-996-2297, fax 312-413-9898 |
#4
|
|||
|
|||
Jeff wrote: this was 3 1/2 years ago. Try more modern news next time. Jeff Thanks for your comment Jeff but I suspect there are still some out there who are not aware of the carcinogenicity of Ritalin. |
#5
|
|||
|
|||
In article . com,
Tim Campbell wrote: Jeff wrote: this was 3 1/2 years ago. Try more modern news next time. Jeff Thanks for your comment Jeff but I suspect there are still some out there who are not aware of the carcinogenicity of Ritalin. Like you, for example. I could only find two studies on the subject, both in rats or mice. The conclusion was that there was little evidence of carcinogenicity from methylphenidate,and in some cases it actually seemed to *reduce* the instance of tumors. -- David Wright :: alphabeta at prodigy.net These are my opinions only, but they're almost always correct. "His staff loves to say Bush is a man who doesn't know the meaning of the word 'quit.' Well, apparently he's not all that conversant with the word 'shame' either." (Will Durst) |
#6
|
|||
|
|||
"Jeff" wrote in message ink.net... this was 3 1/2 years ago. Try more modern news next time. Jeff Pat reply # 43480324885809348790324899348932948932483094834934-3249348903493248-93-24884 FACT is , it was 3 1/2 years ago, and it is STILL being prescribed!!!!!!! http://www.preventcancer.com/patient...id/ritalin.htm American Academy of Pediatrics Guidelines for Treating Behavioral Disorders in Children with Ritalin Ignores Evidence of Cancer Risks warns Samuel S. Epstein, M.D. Chicago, 10/04/01. Based on an industry-funded multi-university trial on 282 pre-teen children treated with Ritalin for attention deficit/hyperactivity disorders (ADHD), just published in Pediatrics, the American Academy of Pediatrics has endorsed the use of the drug. However, the Academy ignores clear evidence of the drug's cancer risks of which parents, teachers and school nurses, besides most pediatricians and psychiatrists, still remain uninformed and unaware. Some 40 years after the drug was first marketed by Ciba Geigy, carcinogenicity tests were conducted at the taxpayers expense by the National Toxicology Program, the results of which were published in 1995. Adult mice were fed Ritalin over a two-year period at dosages close to those prescribed to children. The mice developed a statistically significant incidence of liver abnormalities and tumors, including highly aggressive rare cancers known as hepatoblastomas. These findings are particularly disturbing as the tests were conducted on adult, rather than young mice which would be expected to be much more sensitive to carcinogenic effects. The National Toxicology Program concluded that Ritalin is a "possible human carcinogen," and recommended the need for further research. While still insisting that the drug is safe, the Food and Drug Administration admitted that these findings signal "carcinogenic potential," and required a statement to this effect in the drug's package insert. However, these inserts are not seen by parents or nurses. The Physicians' Desk Reference admits evidence on the carcinogenicity of Ritalin, now manufactured by Novartis, qualified by the statement that "the significance of these results is unknown," apparently not recognizing that this is more alarming than reassuring. Apart from cancer risks, there is also suggestive evidence that Ritalin induces genetic damage in blood cells of Ritalin-treated children. Concerns on Ritalin's cancer risk are more acute in view of the millions of children treated annually with the drug and the escalating incidence of childhood cancer, by some 35% over the last few decades, quite apart from delayed risks of cancer in adult life. These risks are compounded by the availability of alternative safe and effective procedures, notably behavior modification and biofeedback. There is no justification for prescribing Ritalin, even by highly qualified pediatricians and psychiatrists, unless parents have been explicitly informed of the drug's cancer risks. Otherwise, prescribing Ritalin constitutes unarguable medical malpractice. CONTACT: Samuel S. Epstein, M.D. Professor emeritus Environmental & Occupational Medicine Chairman, Cancer Prevention Coalition c/o University of Illinois at Chicago School of Public Health, M/C 922 2121 W. Taylor Street Chicago, IL 60612 phone 312-996-2297, fax 312-413-9898 |
#7
|
|||
|
|||
"David Wright" wrote in message ... In article . com, Tim Campbell wrote: Jeff wrote: this was 3 1/2 years ago. Try more modern news next time. Jeff Thanks for your comment Jeff but I suspect there are still some out there who are not aware of the carcinogenicity of Ritalin. Like you, for example. I could only find two studies on the subject, both in rats or mice. The conclusion was that there was little evidence of carcinogenicity from methylphenidate,and in some cases it actually seemed to *reduce* the instance of tumors. -- David Wright :: alphabeta at prodigy.net These are my opinions only, but they're almost always correct. INCORRECT http://www.pharma.us.novartis.com/pr...ritalin-sr.pdf http://au.geocities.com/neville222/m25ritalin.html http://www.rxlist.com/cgi/generic/methphen_wcp.htm http://www.ritalindeath.com/Package%20insert.htm LL/Jan |
#8
|
|||
|
|||
David Wright wrote: Thanks for your comment Jeff but I suspect there are still some out there who are not aware of the carcinogenicity of Ritalin. Like you, for example. I could only find two studies on the subject, both in rats or mice. The conclusion was that there was little evidence of carcinogenicity from methylphenidate,and in some cases it actually seemed to *reduce* the instance of tumors. "a little evidence of carcinogenicity" is enough for me. |
#9
|
|||
|
|||
"Pace Sanders" wrote in message
David Wright wrote: Thanks for your comment Jeff but I suspect there are still some out there who are not aware of the carcinogenicity of Ritalin. Like you, for example. I could only find two studies on the subject, both in rats or mice. The conclusion was that there was little evidence of carcinogenicity from methylphenidate,and in some cases it actually seemed to *reduce* the instance of tumors. "a little evidence of carcinogenicity" is enough for me. That's not what he said, idiot. And, if you're concerned by this level of risk, you lead a terribly frightened existence. Kill yourself before you are taken by the toxic world that surrounds you. How did you survive this long? moo |
#10
|
|||
|
|||
"LadyLollipop" wrote in message news:w8Yee.61498$WI3.18364@attbi_s71... "David Wright" wrote in message ... In article . com, Tim Campbell wrote: Jeff wrote: this was 3 1/2 years ago. Try more modern news next time. Jeff Thanks for your comment Jeff but I suspect there are still some out there who are not aware of the carcinogenicity of Ritalin. Like you, for example. I could only find two studies on the subject, both in rats or mice. The conclusion was that there was little evidence of carcinogenicity from methylphenidate,and in some cases it actually seemed to *reduce* the instance of tumors. -- David Wright :: alphabeta at prodigy.net These are my opinions only, but they're almost always correct. INCORRECT http://www.pharma.us.novartis.com/pr...ritalin-sr.pdf According to this, the dose was 30 times higher than the maximum dose, based on the weight of the mice. There is no evidence that this occurs in humans. Jeff http://au.geocities.com/neville222/m25ritalin.html http://www.rxlist.com/cgi/generic/methphen_wcp.htm http://www.ritalindeath.com/Package%20insert.htm LL/Jan |
Thread Tools | |
Display Modes | |
|
|
Similar Threads | ||||
Thread | Thread Starter | Forum | Replies | Last Post |
Ritalin and Liver cancer | Tim Campbell | General | 561 | June 17th 05 02:48 PM |
Ritalin Helps Beat Cancer Fatigue | Marciosos6 Probertiosos6 | Kids Health | 211 | December 31st 03 02:06 AM |
Another use for Ritalin | Marciosos7 Probertiosos7 | Kids Health | 8 | December 19th 03 10:22 PM |